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Glypican-2
Summary
- UniProt ID
- Q8BKV1
- Gene Symbol
-
- Gpc2
- Gene ID
- 71951
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- GPI-anchor
- Heparan sulfate
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| side of membrane |
| extracellular region |
| plasma membrane |
| collagen-containing extracellular matrix |
| endoplasmic reticulum |
| Golgi lumen |
| GO Term |
|---|
| smoothened signaling pathway |
| positive regulation of neuron projection development |
| neuron differentiation |
| regulation of signal transduction |
Sequence
MSALRPLLLLLLHLCPGLGPGHGSEAKVVRSCAETRQVLGARGYSLNLIPPSLISGEHLQVCPQEYTCCSSETEQKLIRDAEVTFRGLVEDSGSFLIHTLAARHRKFNEFFREMLSISQHSLAQLFSHSYGRLYSQHAVIFNSLFSGLRDYYEKSGEGLDDTLADFWAQLLERAFPLLHPQYSFPPDFLLCLTRLTSTADGSLQPFGDSPRRLRLQISRALVAARALVQGLETGRNVVSEALKVPVLEGCRQALMRLIGCPLCRGVPSLMPCRGFCLNVAHGCLSSRGLEPEWGGYLDGLLLLAEKLQGPFSFELAAESIGVKISEGLMHLQENSVKVSAKVFQECGTPHPVQSRSRRAPAPREEASRSWRASAEEERPTTAAGTNLHRLVWELRERLSRVRGFWAGLPVTVCGDSRMAADLSQETAPCWTGVGRGRYMSPVVVGSLNEQLHNPELDTSSPDVPTRRRRLHLRAATARMKAAALGQDLDMHDADEDASGSGGGQQYADDWKAGAVPVVPPARPPRPPRPPRRDGLGVRGGSGSARYNQGRSRNLGSSVGLHTPLVLLLLPSALTLLVLR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 55 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 92 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 155 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 498 | O-linked (Xyl...) (heparan sulfate) serine |
|
||
| 500 | O-linked (Xyl...) (heparan sulfate) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Mus musculus |
| HS-GAG biosynthesis | Mus musculus |
| HS-GAG degradation | Mus musculus |
| Retinoid metabolism and transport | Mus musculus |
