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Rho GTPase-activating protein 28

Summary

UniProt ID: Q8BN58
Gene Symbol: Arhgap28 Kiaa1314
Gene ID: 268970
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q8BN58
O-GlcNAcAtlas: Q8BN58
Re-Glyco: Q8BN58

Annotation

Keyword: Alternative splicing GTPase activation Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
signal transduction	IEA	GO_REF
regulation of actin filament polymerization	IBA	GO_REF
regulation of small GTPase mediated signal transduction	IBA	GO_REF
negative regulation of stress fiber assembly	IDA	PMID
negative regulation of stress fiber assembly	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

negative regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

negative regulation of stress fiber assembly

regulation of cellular component biogenesis [inference]

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

negative regulation of stress fiber assembly

regulation of protein-containing complex assembly [inference]

regulation of protein polymerization [inference]

regulation of actin filament polymerization

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

negative regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

negative regulation of stress fiber assembly

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of protein-containing complex assembly [inference]

regulation of protein polymerization [inference]

regulation of actin filament polymerization

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of cytoskeleton organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

regulation of actin filament bundle assembly [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

negative regulation of stress fiber assembly

negative regulation of supramolecular fiber organization [inference]

negative regulation of actin filament bundle assembly [inference]

negative regulation of stress fiber assembly

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of actin filament length [inference]

regulation of actin polymerization or depolymerization [inference]

regulation of actin filament polymerization

Displaying **all 3** entries
GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
cytoplasm	IBA	GO_REF
cell junction	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying **all 2** entries
GO Term	Evidence Code	Reference
GTPase activator activity	ISS	PMID
GTPase activator activity	IBA	GO_REF

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEVEDSGGVVLTAYHSHARSQPQGAEPRCASRASHPLSRKSIPRCRRINRMLSNESLHPPSFSRSNSQASVDSSASMEEFLREIESIKESSVGASQEQPPTAAAAAAEVKPVDEGELEAEWLQDVGLSTLISGNEEEDGKALLSTLTRTQAAAVKKRYNTYTQTLRKKNKQPVRDVRDIFGVSESPPSDSCEHATQLDGTKEEKDLPGVTKTSRPLPDDASLSSTTLSNGAQDEEGGFVALQSGSVSILEAIPDIAVHTNGSADAEQSVQSTLSDDDYHGKNVPAEAEELSFEVSYSEMVTEMPDRNKWKKSDIKKEDYVLTKFIIQKTRFGLTETGDLSVEDMKKIRHLSLIELTAFFDAFGIQLKRNKTERVRGRDNGIFGVPLTVLLDNDRKKDPAVKVPLVLQKFFQKVEESGLESEGIFRLSGCTAKVKQYREELDARFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPDIKVQFQALHLMVMALPDANRDTAQALMAFFNKVIANESKNRMNLWNISTVMAPNLFFSRSKHSDCEELLLANTATHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSMKKLLRRKTLDREVSILKTSKVPQKSPSSRRMSDVPEGVIRVHAPLLSKVSMAIQLNSQTKAKDILAKFQYENSHGSSEHIKMQNQRLYEVGGNIGQHCLDPDAYILDVYHINPHAEWVIKP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites