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MIRAGE
5'-AMP-activated protein kinase catalytic subunit alpha-2
Summary
- UniProt ID
- Q8BRK8
- Gene Symbol
- Prkaa2
- Gene ID
- 108079
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- ATP-binding Autophagy Biological rhythms Cholesterol biosynthesis Chromatin regulator Cytoplasm Fatty acid biosynthesis Magnesium Metal-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription regulation Ubl conjugation Wnt signaling pathway
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytoplasmic translation | ||
| protein phosphorylation | ||
| protein phosphorylation | ||
| fatty acid biosynthetic process |
|
|
| phosphatidylethanolamine biosynthetic process |
GO Hierarchy
- rhythmic process
- regulation of circadian rhythm
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| chromatin binding | ||
| protein kinase activity | ||
| protein kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity |
GO Hierarchy
Sequence
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKACDIMAEVYRAMKQLGFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDSRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGLHRARSSFDSSTAENHSLSGSLTGSLTGSTLSSASPRLGSHTMDFFEMCASLITALAR
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AMPK inhibits chREBP transcriptional activation activity | Mus musculus |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | Mus musculus |
| Carnitine shuttle | Mus musculus |
| Energy dependent regulation of mTOR by LKB1-AMPK | Mus musculus |
| Macroautophagy | Mus musculus |
| Nuclear events mediated by NFE2L2 | Mus musculus |
| Regulation of TP53 Activity through Phosphorylation | Mus musculus |
| TP53 Regulates Metabolic Genes | Mus musculus |
