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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Summary

UniProt ID

Q8BTI9

Gene Symbol

Pik3cb

Organism

Mus musculus (house mouse)

External Links

GlyGen: Q8BTI9
PubChem: Q8BTI9
O-GlcNAcAtlas: Q8BTI9

Annotation

Keyword

3D-structure
ATP-binding
Autophagy
Cell adhesion
Cytoplasm
Endocytosis
Kinase
Lipid metabolism
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying entries **21 - 27** of 27 in total

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GO Term
homophilic cell adhesion via plasma membrane adhesion molecules
phosphatidylinositol-mediated signaling
positive regulation of Rac protein signal transduction
negative regulation of MAPK cascade
negative regulation of vascular endothelial growth factor signaling pathway
negative regulation of sprouting angiogenesis
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway

Displaying **all 10** entries
GO Term
nucleus
nucleolus
cytoplasm
plasma membrane
midbody
brush border membrane
cytosol
nucleoplasm
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA

Displaying **all 7** entries
GO Term
kinase activity
insulin receptor substrate binding
1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
1-phosphatidylinositol-3-kinase activity
ATP binding
1-phosphatidylinositol-4-phosphate 3-kinase activity
protein serine kinase activity

Annotation information from UniProt.

Sequence

MPPAMADNLDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAEKLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEAKIQSLVGLSWIDWLKHTYPPEHEPSVLENLEDKLYGGKLVVAVHFENSQDVFSFQVSPNLNPIKINELAIQKRLTIRGKEDEASPCDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYAENATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLSRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites