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Inositol-tetrakisphosphate 1-kinase

Summary

UniProt ID: Q8BYN3
Gene Symbol: Itpk1
Gene ID: 217837
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q8BYN3
PubChem: Q8BYN3
Re-Glyco: Q8BYN3

Annotation

Keyword: ATP-binding Acetylation Hydrolase Isomerase Kinase Magnesium Metal-binding Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
neural tube development	IMP	PMID
inositol trisphosphate metabolic process	IEA	GO_REF
necroptotic process	ISS	GO_REF
necroptotic process	ISO	GO_REF
necroptotic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

inositol phosphate metabolic process [inference]

inositol trisphosphate metabolic process

organophosphate metabolic process [inference]

inositol phosphate metabolic process [inference]

inositol trisphosphate metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

inositol phosphate metabolic process [inference]

inositol trisphosphate metabolic process

cell death [inference]

programmed cell death [inference]

programmed necrotic cell death [inference]

necroptotic process

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

neural tube development

tube development [inference]

neural tube development

Displaying 1 entry
GO Term	Evidence Code	Reference
apical plasma membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
magnesium ion binding	IEA	GO_REF
inositol-1,3,4,5-tetrakisphosphate 6-kinase activity	ISS	GO_REF
inositol-1,3,4,5-tetrakisphosphate 6-kinase activity	ISO	GO_REF
inositol-1,3,4,5-tetrakisphosphate 6-kinase activity	IEA	GO_REF
ATP binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

inositol phosphate kinase activity [inference]

inositol tetrakisphosphate kinase activity [inference]

inositol trisphosphate kinase activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

inositol tetrakisphosphate kinase activity [inference]

inositol trisphosphate kinase activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MQTFLKGKRVGYWLSEKKVKKLNFQAFAELCRKRGIEVVQLNLSRPIEEQGPLDVIIHKLTDVILEADQNDSQSLELVHRFQEYIDAHPETIVLDPLPAIRTLLDRSKSYELIRKIEAYMKDDRICSPPFMELTSLCGEDTMRLLEQNGLAFPFICKTRVAHGTNSHEMAIVFNQEGLNAIQPPCVVQNFINHNAVLYKVFVVGESYTVVQRPSLKNFSAGTSDRESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIRELSRALRQALGVSLFGIDIIINNQTGQHAVIDVNAFPGYEGVSEFFTDLLNHIATVLQGQSTGGAATEEVAPLRHNRLLAEPAGSLAGERTCSASPGCCGSMKGQDTPWKTETEAGNMGAGASAKLPHQRLGCTTGVSPSFQQHCVASLATKASSQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
42			G31852PQ	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Factors involved in megakaryocyte development and platelet production	Mus musculus
Synthesis of IP3 and IP4 in the cytosol	Mus musculus
Synthesis of pyrophosphates in the cytosol	Mus musculus

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Acknowledgements