GlyCosmos Portal

Submissions

GDH/6PGL endoplasmic bifunctional protein

Summary

UniProt ID: Q8CFX1
Gene Symbol: H6pd
Gene ID: 100198
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0006643

GlyConnect

GDH/6PGL endoplasmic bifunctional protein

GlyGen

Q8CFX1

PubChem

Q8CFX1

O-GlcNAcAtlas

Q8CFX1

Re-Glyco

Q8CFX1

Annotation

Keyword: Endoplasmic reticulum Glucose metabolism Glycoprotein Hydrolase Multifunctional enzyme NAD NADP Oxidoreductase Pyrrolidone carboxylic acid Reference proteome Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
glucose metabolic process	IEA	GO_REF
pentose-phosphate shunt	IDA	PMID
pentose-phosphate shunt	IEA	GO_REF GO_REF GO_REF
NADP+ metabolic process	ISO	GO_REF
NADP+ metabolic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP+ metabolic process

NADPH regeneration [inference]

carbohydrate derivative metabolic process [inference]

pentose-phosphate shunt, oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

response to stimulus [inference]

response to nutrient levels

response to chemical [inference]

response to oxygen-containing compound [inference]

response to alcohol

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of hormone biosynthetic process [inference]

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of ketone metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of hormone metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of hormone biosynthetic process [inference]

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of alcohol biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of steroid biosynthetic process [inference]

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

regulation of hormone biosynthetic process [inference]

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

regulation of cortisol biosynthetic process

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
endoplasmic reticulum	IMP	PMID
endoplasmic reticulum	IBA	GO_REF
endoplasmic reticulum	IEA	GO_REF
endoplasmic reticulum lumen	ISS	GO_REF
endoplasmic reticulum lumen	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

sarcoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

sarcoplasmic reticulum

Displaying entries **1 - 5** of 15 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
glucose-6-phosphate dehydrogenase activity	ISO	GO_REF GO_REF
glucose-6-phosphate dehydrogenase activity	EXP	PMID
glucose-6-phosphate dehydrogenase activity	IDA	PMID
glucose-6-phosphate dehydrogenase activity	IMP	PMID
glucose-6-phosphate dehydrogenase activity	IEA	GO_REF GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

glucose dehydrogenase activity [inference]

glucose 1-dehydrogenase [NAD(P)+] activity [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

glucose-6-phosphate dehydrogenase activity

glucose 1-dehydrogenase [NAD(P)+] activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

6-phosphogluconolactonase activity

binding [inference]

carbohydrate binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLLAAMCLALLGCLQAQELKGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKVLESLSCPKDLVPSRCDELKGQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRIFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETIDAEGRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAAVLQHKLWAFQALRGLQKSSAILGQYQAYSGQVRRELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNRAYCTQSERHWVPEQSRCLPQQIIFYIGHGELGHPAILVSRNLFKPSLPTQKWKEVQDQPGLRLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLAFEVPRPYPGGAENGQLLDFEFSGGQLTFSQQQLEVLIPDLGSVPKPSDFQVLGARYRQSPLITAWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPTGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
154	N-linked (GlcNAc...) asparagine	30899004	G62765YT G39188ZX G06110VR	UniProt GlyGen GlyConnect
155			G49108TO	GlyGen
156			G49108TO	GlyGen
279	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
681	N-linked (GlcNAc...) asparagine			UniProt GlyGen