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Complement C1r-A subcomponent
Summary
- UniProt ID
- Q8CG16
- Gene Symbol
-
- C1ra
- C1r
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Complement pathway
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Hydroxylation
- Phosphoprotein
- Reference proteome
- Repeat
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| innate immune response |
| zymogen activation |
| complement activation, classical pathway |
| GO Term |
|---|
| extracellular space |
| blood microparticle |
| GO Term |
|---|
| calcium ion binding |
| serine-type endopeptidase activity |
Sequence
MWLFALLVTLFYGVEGSIYLPQKLYGEVTSPLYPKPYPSDLETTTVITVPMGYRVKLVFWQFDVEPSEGCFYDYVKISADKQTLGRFCGQLDSPLGNPPGSKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASQPNSVEEGLQPRCQHLCHNYVGGYFCSCHPGYELQKDGQSCQAECSSELYTEPSGYVSSLEYPQPYPPDLRCNYSIRVERGLTVHLKFLDPFEIDDHQQVHCPYDQLQIYANGKNLGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLHYTTETIKCPQPKALDEFTIIQDPQPQYQFRDYFIVTCKQGYQLMEGNQALLSFTAVCQNDGTWHRAMPRCKIKNCGQPQSLSNGDFRYITTKGVTTYEASIQYHCHEPYYKMLTRAGSSESMRGIYTCTAQGIWKNEEEGEKMPRCLPVCGKPVNPVTQKERIIRGQPARPGNFPWQAFTTTHGRGGGALLGDRWILTAAHTIYPKHHNKENDNANPKMLVFLGHTNVEQIKKLGHHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPELLPICLPDNETFYGQGLMGYVSGFGITEDKLAFDLRFVRLPVADSEACQRWLQTKKDTSPFSQNMFCSGDPAVQQDACQGDSGGVFAVRDRNRDIWVATGIVSWGIGCGEGYGFYTKVLNYVDWIKKEMGDEN
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Classical antibody-mediated complement activation | Mus musculus |
| Initial triggering of complement | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
