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Rap guanine nucleotide exchange factor 2

Summary

UniProt ID: Q8CHG7
Gene Symbol: Rapgef2 Kiaa0313 Pdzgef1
Gene ID: 76089
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q8CHG7
The O-GlcNAc Database: Q8CHG7
O-GlcNAcAtlas: Q8CHG7
Re-Glyco: Q8CHG7

Annotation

Keyword: Cell junction Cell membrane Cytoplasm Developmental protein Differentiation Endosome GTPase activation Guanine-nucleotide releasing factor Neurogenesis Phosphoprotein Reference proteome Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 82 in total

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GO Term	Evidence Code	Reference
blood vessel development	IMP	PMID
neuron migration	IMP	PMID
G protein-coupled receptor signaling pathway	ISO	GO_REF
G protein-coupled receptor signaling pathway	IDA	PMID
G protein-coupled receptor signaling pathway	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

brain-derived neurotrophic factor receptor signaling pathway

neurotrophin signaling pathway [inference]

nerve growth factor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

neuropeptide signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction [inference]

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

establishment of endothelial intestinal barrier

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development

cell motility [inference]

cell migration [inference]

neuron migration

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to oxygen-containing compound [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

developmental process [inference]

anatomical structure development [inference]

blood vessel development

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

establishment of endothelial intestinal barrier

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development

system development [inference]

ventricular system development

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier

establishment of endothelial intestinal barrier

neuron development [inference]

central nervous system neuron development [inference]

forebrain neuron development

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

response to nerve growth factor [inference]

cellular response to nerve growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

response to chemical [inference]

response to organophosphorus [inference]

response to cAMP [inference]

cellular response to cAMP

response to cGMP [inference]

cellular response to cGMP

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to oxygen-containing compound [inference]

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to cGMP [inference]

cellular response to cGMP

cellular response to nitrogen compound [inference]

response to oxygen-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to cGMP [inference]

cellular response to cGMP

cellular response to oxygen-containing compound [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to oxygen-containing compound [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

regulation of neuron migration [inference]

positive regulation of neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

positive regulation of cell differentiation [inference]

positive regulation of vasculogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of vasculogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of dendrite morphogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendrite morphogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

positive regulation of cell differentiation [inference]

positive regulation of vasculogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of vasculogenesis [inference]

positive regulation of vasculogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of vasculogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

brain-derived neurotrophic factor receptor signaling pathway

neurotrophin signaling pathway [inference]

nerve growth factor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

neuropeptide signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of secondary metabolic process [inference]

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of cAMP-dependent protein kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of cAMP-dependent protein kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of cAMP-dependent protein kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of cAMP-dependent protein kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

regulation of leukocyte apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

regulation of dendritic cell apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of microvillus assembly [inference]

positive regulation of microvillus assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

regulation of cell junction assembly

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

positive regulation of cell differentiation [inference]

positive regulation of vasculogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of vasculogenesis [inference]

positive regulation of vasculogenesis

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of leukocyte apoptotic process [inference]

positive regulation of dendritic cell apoptotic process

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

positive regulation of cell differentiation [inference]

positive regulation of vasculogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of dendrite morphogenesis

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of dendrite morphogenesis

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of microvillus assembly [inference]

positive regulation of microvillus assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of microvillus organization [inference]

regulation of microvillus assembly [inference]

positive regulation of microvillus assembly

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of microvillus assembly [inference]

positive regulation of microvillus assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

regulation of synapse organization [inference]

regulation of modification of synaptic structure [inference]

regulation of modification of postsynaptic structure

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of dendrite morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of microvillus assembly

regulation of cell junction assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

regulation of neuron migration [inference]

positive regulation of neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of dendrite morphogenesis

regulation of biological quality [inference]

regulation of synaptic plasticity

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

positive regulation of binding [inference]

positive regulation of protein binding

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of cAMP-dependent protein kinase activity [inference]

positive regulation of cAMP-dependent protein kinase activity

regulation of binding [inference]

regulation of protein binding [inference]

positive regulation of protein binding

positive regulation of binding [inference]

positive regulation of protein binding

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	Reference
cytoplasm	ISS	GO_REF
cytoplasm	ISO	GO_REF
cytoplasm	IEA	GO_REF GO_REF
late endosome	ISS	GO_REF
late endosome	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

synapse

anchoring junction [inference]

cell-cell junction

tight junction [inference]

bicellular tight junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

endocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

endocytic vesicle

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	Reference
guanyl-nucleotide exchange factor activity	ISS	GO_REF
guanyl-nucleotide exchange factor activity	ISO	GO_REF
guanyl-nucleotide exchange factor activity	IDA	PMID
guanyl-nucleotide exchange factor activity	IMP	PMID PMID
guanyl-nucleotide exchange factor activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

adrenergic receptor binding [inference]

beta-1 adrenergic receptor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein domain specific binding [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidic acid binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

cyclic nucleotide binding [inference]

cAMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKPLAAPANHGVLGQQEKQSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSCSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPAALPVSGTLSSSNPDLLQSHHRILDFSTTPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPEQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLKSKTSCANLKKFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLSGQNLQPPVIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSANATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATSTLPKNPGDKKPVKSETSPVAPRAGPQQKVQPQQPLAQPQPPHKVSQGLQVPAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHRKQAEDTISNASSQLSSPPTSPQSSPRKGYALALSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVESNLGVGRMERRTLMEPDQYSLGSYAPVSESRGLYAAATVISSPSTEELSHDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDAASIWASGGHMDQMMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSAEAESSSMVPVTTEEAKPVPMPAHIAVTPSTTKGLIARKEGRYREPPPTPPGYVGIPIADFPEGPCHPARKPPDYNVALQRSRMVARPTEAPAPGQTPPAAAASRPGSKPQWHKPSDADPRLAPFQPQGFAGAEEDEDEQVSAV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 18 in total

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Position	PubMed ID	GlyTouCan ID	Source
1006		G49108TO	GlyGen
1155	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
1158	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
1161	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
1165	22517741 22645316 36852467 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
1192	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
1208		G49108TO	GlyGen
1247	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
1352	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database
1357	22517741 22645316 36852467 40021952 40885482	G49108TO	The O-GlcNAc Database