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Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

Summary

UniProt ID: Q8CHK3
Gene Symbol: Bb1 Leng4 Lpiat1 Mboat7 Oact7
Gene ID: 77582
Organism: Mus musculus (house mouse)

External Links

GlyGen

Q8CHK3

PubChem

Q8CHK3

SwissLipids

SLP:000000285

Re-Glyco

Q8CHK3

Annotation

Keyword: Acyltransferase Endoplasmic reticulum Glycoprotein Phospholipid biosynthesis Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
phosphatidylinositol biosynthetic process	ISS	GO_REF
phosphatidylinositol biosynthetic process	ISO	GO_REF
phosphatidylinositol biosynthetic process	IBA	GO_REF
phosphatidylinositol biosynthetic process	IEA	GO_REF
ventricular system development	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

phosphatidylinositol metabolic process

biosynthetic process [inference]

phosphatidylinositol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

lipid modification

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine acyl-chain remodeling

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

layer formation in cerebral cortex

anatomical structure development [inference]

system development [inference]

ventricular system development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of triglyceride metabolic process

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
endoplasmic reticulum	ISO	GO_REF
endoplasmic reticulum	IEA	GO_REF
endoplasmic reticulum membrane	ISS	GO_REF
endoplasmic reticulum membrane	ISO	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

organelle membrane contact site [inference]

mitochondria-associated endoplasmic reticulum membrane contact site

Displaying **all 3** entries
GO Term	Evidence Code	Reference
O-acyltransferase activity
lysophospholipid acyltransferase activity	IMP	PMID
lysophospholipid acyltransferase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTPEEWTYLMVLLISIPVGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEIASGFHKEPTLGLLPEVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPEAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPTRLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYETIRNIDCYGTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPFRSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCLAAEGYLESALRRHLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSMADTLRYWASIYFWVHFLALACLGLGLVLGGGSPSKRKTPSQATSSQAKEKLREE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
98				GlyGen
321	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Acyl chain remodelling of PI	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10908	hydrocephalus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements