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Melatonin receptor type 1B

Summary

UniProt ID: Q8CIQ6
Gene Symbol: Mtnr1b
Gene ID
Organism: Mus musculus (house mouse)

External Links

Re-Glyco: Q8CIQ6

Annotation

Keyword: Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
G protein-coupled receptor signaling pathway	IBA	GO_REF
G protein-coupled receptor signaling pathway	IEA	GO_REF
circadian rhythm	TAS	PMID
negative regulation of receptor guanylyl cyclase signaling pathway	ISO	GO_REF
glucose homeostasis	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

rhythmic process [inference]

circadian rhythm

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of circadian rhythm [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

regulation of circadian sleep/wake cycle, non-REM sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of circadian rhythm

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of biological process [inference]

positive regulation of circadian rhythm

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of transmission of nerve impulse

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of transmission of nerve impulse

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of peptide secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

negative regulation of vasoconstriction

negative regulation of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

positive regulation of cell communication [inference]

positive regulation of transmission of nerve impulse

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of transmission of nerve impulse

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of transmission of nerve impulse [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of transmission of nerve impulse

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of receptor guanylyl cyclase signaling pathway

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of transmission of nerve impulse

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of protein secretion [inference]

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

negative regulation of protein secretion [inference]

negative regulation of insulin secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

regulation of circadian sleep/wake cycle, non-REM sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, non-REM sleep

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse

negative regulation of vasoconstriction

regulation of action potential [inference]

regulation of neuronal action potential

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of insulin secretion

negative regulation of peptide hormone secretion [inference]

negative regulation of insulin secretion

regulation of membrane potential [inference]

regulation of action potential [inference]

regulation of neuronal action potential

negative regulation of cytosolic calcium ion concentration

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

Displaying **all 3** entries
GO Term	Evidence Code	Reference
plasma membrane	ISA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
G protein-coupled receptor activity	IBA	GO_REF
G protein-coupled receptor activity	IEA	GO_REF
melatonin receptor activity	ISA	PMID
melatonin receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

melatonin receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPENSSIPNCCEASGLAARPSWSGSAGARPPVTARAPWVAPMLSTVVVVTTAVDFVGNLLVILSVLRNRKLRNAGNLFVVSLALADLVIALYPYPLILVAIIRDGWVLGEAHCKASAFVMGLSVIGSVFNITAIAINRYCCICHSTTYHRVCSHWYTPIYISLVWLLTLVALVPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVAIHFLLPMAVVSFCYLRIWVLVLQARRKAKATRKLRLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQVPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILLAIWNTRRCIQHASKHCLTEERQGPTPPAARATVPVKEGAL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
4	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Class A/1 (Rhodopsin-like receptors)	Mus musculus
G alpha (i) signalling events	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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