Prostaglandin G/H synthase 1

Summary
UniProt ID
Q8HZR1
Gene Symbol
  • COX1
  • PTGS1
Gene ID
403544
Organism
Canis lupus familiaris (dog)
PubChem
Q8HZR1
Re-Glyco
Q8HZR1
Annotation
Keyword
  • Alternative splicing
  • Dioxygenase
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Heme
  • Membrane
  • Microsome
  • Peroxidase
  • Prostaglandin biosynthesis
  • Reference proteome
  • Signal
Gene Ontology (GO)
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
response to oxidative stress
cyclooxygenase pathway
Sequence
MSRGSRLHRWPLLLLLLLLLPPPPVLPAEARTPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPELWTWLRNSLRPSPSFLHFLLTHGRWFWEFINATFIRDMLMRLVLTARSNLIPSPPTYNIAHDYISWESFSNVSYYTRVLPSVPQDCPTPMGTKGKKQLPDAQLLGRRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLDRQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGILPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFSAQFQYRNRIAMEFNQLYHWHPLMPDSFWVGSQEYSYEQFLFNTSMLTHYGIEALVDAFSRQSAGRIGGGRNIDHHVLHVAVETIKESRELRLQPFNEYRKRFGMRPYMSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEMGFNMVKTATLKKLVCLNTKTCPYVSFRVPDPHQDGGPGVERPSTEL
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
71 N-linked (GlcNAc...) asparagine
107 N-linked (GlcNAc...) asparagine
147 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
COX reactions Canis familiaris
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Canis familiaris

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025