Coagulation factor VII

Summary
UniProt ID
Q8K3U6
Gene Symbol
F7
Gene ID
260320
Organism
Rattus norvegicus (Norway rat)
PubChem
Q8K3U6
Re-Glyco
Q8K3U6
Annotation
Keyword
Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hydroxylation Reference proteome Repeat Secreted Serine protease Signal Zymogen
Gene Ontology (GO)
GO Hierarchy
Sequence
MVPQTHGLLLLYFLLQLQGPLGAVVFITQEEAHGVLHRQRRANSLLEELWSSSLERECNEERCSFEEAREIFKSPERTKQFWTIYSDGDQCASNPCQNGGTCQDHLKSYVCFCPLDFEGRNCEKNKNEQLICANENGDCDQYCRDHVGTKRTCSCHEDYVLQPDEVSCKPKVEYPCGRIPVVEKRNFSRPQGRIVGGYVCPKGECPWQAVLKFNEALLCGAVLLDTRWIVTAAHCFDKFGKLVNITVVLGEHDFSEKEGTEQVRLVEQVIMPNKYTRGRTDHDIALVRLHRPVTFTDYVVPLCLPERAFSENTLASIRFSRVSGWGQLLDRGATALELMVIEVPRLMTQDCLEHAKHSANTPRITENMFCAGYMDGTKDACKGDSGGPHATHYHGTWYLTGVVSWGEGCAAIGHIGVYTRVSQYIDWLVKYMDSKLRVGISRVSLL
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
93
  • O-linked (Glc...) serine; alternate
  • O-linked (Xyl...) serine; alternate
101
  • O-linked (Fuc) threonine
186
  • N-linked (GlcNAc...) asparagine
244
  • N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:2841 asthma
DOID:9352 type 2 diabetes mellitus
DOID:9351 diabetes mellitus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026