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MIRAGE
Rho guanine nucleotide exchange factor 6

Summary
UniProt ID
Q8K4I3
Gene Symbol
  • Arhgef6
Gene ID
73341
Organism
Mus musculus (house mouse)
GlyGen
Q8K4I3
PubChem
Q8K4I3
The O-GlcNAc Database
Q8K4I3
RaftProt
Q8K4I3
O-GlcNAcAtlas
Q8K4I3
Re-Glyco
Q8K4I3
Annotation
Keyword
  • 3D-structure
  • Cell projection
  • Guanine-nucleotide releasing factor
  • Phosphoprotein
  • Reference proteome
  • SH3 domain
Gene Ontology (GO)
Displaying all 2 entries
GO Term
cell-cell junction
lamellipodium
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
guanyl-nucleotide exchange factor activity
Annotation information from UniProt.
Sequence
MNPEERLVTWLISLGVLESPKKTVCDPEEFLKSSLKNGVVLCKLINRLLPGSVEKYCLEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSAATSSQTNPQVAVPSTAPEQHSEEKAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAIKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNRLDEIEGSDCMFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPTSCGSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKASEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
550
558
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 7 entries
Pathway Name Organism
CDC42 GTPase cycle Mus musculus
G alpha (12/13) signalling events Mus musculus
G beta:gamma signalling through CDC42 Mus musculus
NRAGE signals death through JNK Mus musculus
RAC1 GTPase cycle Mus musculus
RHOU GTPase cycle Mus musculus
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Mus musculus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025