GlyCosmos Portal

Submissions

Xylosyl- and glucuronyltransferase LARGE2

Summary

UniProt ID: Q8N3Y3
Gene Symbol: LARGE2 GYLTL1B PP5656
Gene ID: 120071
Organism: Homo sapiens (human)

External Links

GlycoProtDB

GPDB0012388

GlyConnect

Glycosyltransferase-like protein LARGE2

GlyGen

Q8N3Y3

PubChem

Q8N3Y3

Re-Glyco

Q8N3Y3

Annotation

Keyword: Glycoprotein Glycosyltransferase Golgi apparatus Manganese Metal-binding Multifunctional enzyme Proteomics identification Reference proteome Signal-anchor Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
protein O-linked glycosylation	TAS	Reactome
protein O-linked glycosylation via mannose	IDA	PMID
protein O-linked glycosylation via mannose	IBA	GO_REF
protein O-linked glycosylation via mannose	IEA	GO_REF GO_REF
muscle cell cellular homeostasis	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation

protein O-linked glycosylation via mannose

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

Displaying **all 4** entries
GO Term	Evidence Code	Reference
Golgi membrane	EXP	PMID
Golgi membrane	TAS	Reactome Reactome Reactome
Golgi membrane	IEA	GO_REF
Golgi apparatus	IBA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	Reference
glucuronosyltransferase activity	ISS	GO_REF
glucuronosyltransferase activity	TAS	Reactome
glucuronosyltransferase activity	IBA	GO_REF
glucuronosyltransferase activity	IEA	GO_REF
manganese ion binding	TAS	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

glucuronosyltransferase activity

pentosyltransferase activity [inference]

xylosyltransferase activity

UDP-xylosyltransferase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLPRGRPRALGAAALLLLLLLLGFLLFGGDLGCERREPGGRAGAPGCFPGPLMPRVPPDGRLRRAAALDGDPGAGPGDHNRSDCGPQPPPPPKCELLHVAIVCAGHNSSRDVITLVKSMLFYRKNPLHLHLVTDAVARNILETLFHTWMVPAVRVSFYHADQLKPQVSWIPNKHYSGLYGLMKLVLPSALPAELARVIVLDTDVTFASDISELWALFAHFSDTQAIGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLRLDRLRQAGWEQMWRLTARRELLSLPATSLADQDIFNAVIKEHPGLVQRLPCVWNVQLSDHTLAERCYSEASDLKVIHWNSPKKLRVKNKHVEFFRNFYLTFLEYDGNLLRRELFVCPSQPPPGAEQLQQALAQLDEEDPCFEFRQQQLTVHRVHVTFLPHEPPPPRPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLHFVEASPVLAARQDVAYHVVYREGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLGLGSRRKAALVVPAFETLRYRFSFPHSKVELLALLDAGTLYTFRYHEWPRGHAPTDYARWREAQAPYRVQWAANYEPYVVVPRDCPRYDPRFVGFGWNKVAHIVELDAQEYELLVLPEAFTIHLPHAPSLDISRFRSSPTYRDCLQALKDEFHQDLSRHHGAAALKYLPALQQPQSPARG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
80	N-linked (GlcNAc...) asparagine	29741879 37074911	G11101UV G83229XP G76295SF G46503DX	GlycoProtDB UniProt GlyGen GlyConnect
107	N-linked (GlcNAc...) asparagine		G02815KT	UniProt GlyGen
231	N-linked (GlcNAc...) asparagine			UniProt GlyGen