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SID1 transmembrane family member 2

Summary

UniProt ID: Q8NBJ9
Gene Symbol: CGI-40 PSEC0072 SIDT2 UNQ685/PRO1325
Gene ID: 51092
Organism: Homo sapiens (human)

External Links

GlyGen: Q8NBJ9
The O-GlcNAc Database: Q8NBJ9
Re-Glyco: Q8NBJ9

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane DNA-binding Direct protein sequencing Glycoprotein Lysosome Phosphoprotein Proteomics identification RNA-binding Reference proteome Signal Transmembrane helix Transport

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
cell morphogenesis
type B pancreatic cell development
RNA catabolic process	ISS	GO_REF
RNA catabolic process	IEA	GO_REF
response to glucose

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

nucleic acid catabolic process [inference]

RNA catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

nucleic acid catabolic process [inference]

RNA catabolic process

cell population proliferation [inference]

epithelial cell proliferation [inference]

type B pancreatic cell proliferation

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

type B pancreatic cell development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

type B pancreatic cell development

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

type B pancreatic cell development

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to chemical [inference]

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

localization [inference]

establishment of localization [inference]

transport [inference]

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport

establishment of RNA localization [inference]

RNA transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular localization [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of cellular localization [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of protein secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion [inference]

regulation of insulin secretion involved in cellular response to glucose stimulus

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GO Term	Evidence Code	Reference
lysosome	IDA	PMID
lysosome	IBA	GO_REF
lysosome	IEA	GO_REF
lysosomal membrane	EXP	PMID
lysosomal membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

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GO Term	Evidence Code	Reference
DNA binding
double-stranded RNA binding	IBA	GO_REF
double-stranded RNA binding	IEA	GO_REF
AP-2 adaptor complex binding	ISS	GO_REF
AP-2 adaptor complex binding	IEA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

nucleobase-containing compound transmembrane transporter activity [inference]

nucleic acid transmembrane transporter activity

RNA transmembrane transporter activity

macromolecule transmembrane transporter activity [inference]

nucleic acid transmembrane transporter activity

RNA transmembrane transporter activity

binding [inference]

nucleic acid binding [inference]

DNA binding

RNA binding [inference]

double-stranded RNA binding

protein-containing complex binding [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MFALGLPFLVLLVASVESHLGVLGPKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQKKKTLLVAIDRACPESGHPRVLADSFPGSSPYEGYNYGSFENVSGSTDGLVDSAGTGDLSYGYQGRSFEPVGTRPRVDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
27	N-linked (GlcNAc...) asparagine			UniProt GlyGen
54	N-linked (GlcNAc...) asparagine	24190977	G80479JV	UniProt GlyGen
60	N-linked (GlcNAc...) asparagine			UniProt GlyGen
123	N-linked (GlcNAc...) asparagine			UniProt GlyGen
141	N-linked (GlcNAc...) asparagine			UniProt GlyGen
165	N-linked (GlcNAc...) asparagine	24190977 37074911	G75006KF G57776ZS G86880BF G27947YN G00912UN G59626AS	UniProt GlyGen
198		38253038	G49108TO	The O-GlcNAc Database
476	N-linked (GlcNAc...) asparagine			UniProt GlyGen
496	N-linked (GlcNAc...) asparagine			UniProt GlyGen
572	N-linked (GlcNAc...) asparagine			UniProt GlyGen