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Integrin beta-3
Summary
- UniProt ID
- Q8R2H2
- Gene Symbol
- Itgb3
- Gene ID
- 29302
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Calcium Cell adhesion Cell junction Cell membrane Cell projection Disulfide bond EGF-like domain Glycoprotein Integrin Magnesium Metal-binding Phosphoprotein Postsynaptic cell membrane Reference proteome Repeat Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| positive regulation of endothelial cell proliferation | ||
| positive regulation of endothelial cell proliferation | ||
| positive regulation of cell-matrix adhesion | ||
| positive regulation of leukocyte migration | ||
| positive regulation of leukocyte migration |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of cell adhesion [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
regulation of cell motility [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| nucleus | ||
| nucleus | ||
| nucleoplasm |
|
|
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | Reference |
|---|---|---|
| fibronectin binding | ||
| fibronectin binding | ||
| fibronectin binding | ||
| protease binding | ||
| protease binding |
Sequence
MRTRRPGQLWATLLALGALAGVVVGESNICTTRGVNSCQQCLAVSPVCAWCSDESLPQNSPRCNLKKNLLKDKCSPESIEFPVSEAQILEALPLSSKGSGDSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMFISPPQAIKNPCYTMKSTCLPMFGYKHVLTLTDQVTRFNDEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGRCHIGPDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCVGLKIGDTVSFSIEAKVRGCPQQKEQSFTIKPVGFKDSLTVQVTFDCDCDCQAFAQPLSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPSQQEECSPKEGQPICSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQPGSYGDTCEKCPTCPDACSFKKDCVECKKFNRGKLHEENNCNRFCRDDIELVKELTDTGKNAVNCTYKNEDDCVVRFQYYEDSSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Rattus norvegicus |
| Elastic fibre formation | Rattus norvegicus |
| Fibrin formation | Rattus norvegicus |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Rattus norvegicus |
| Integrin cell surface interactions | Rattus norvegicus |
| Integrin signaling | Rattus norvegicus |
| MAP2K and MAPK activation | Rattus norvegicus |
| Molecules associated with elastic fibres | Rattus norvegicus |
| PECAM1 interactions | Rattus norvegicus |
| Platelet degranulation | Rattus norvegicus |
