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CD109 antigen

Summary

UniProt ID: Q8R422
Gene Symbol: Cd109
Gene ID: 235505
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0006881
GlyGen: Q8R422
Re-Glyco: Q8R422

Annotation

Keyword: Bait region Cell membrane Disulfide bond GPI-anchor Reference proteome Serine protease inhibitor Signal Thioester bond

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
hair follicle development	IMP	PMID
negative regulation of keratinocyte proliferation	IMP	PMID
negative regulation of transforming growth factor beta receptor signaling pathway	ISO	GO_REF
negative regulation of transforming growth factor beta receptor signaling pathway	IEA	GO_REF
regulation of keratinocyte differentiation	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell-cell fusion [inference]

syncytium formation by cell-cell fusion [inference]

osteoclast fusion

multicellular organismal process [inference]

molting cycle process [inference]

hair cycle process [inference]

hair follicle development

developmental process [inference]

anatomical structure development [inference]

hair follicle development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of keratinocyte proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of wound healing

negative regulation of response to wounding [inference]

negative regulation of wound healing

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of wound healing

negative regulation of response to wounding [inference]

negative regulation of wound healing

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

negative regulation of wound healing

negative regulation of response to wounding [inference]

negative regulation of wound healing

regulation of cellular response to growth factor stimulus [inference]

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of epidermis development [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of keratinocyte proliferation

regulation of epithelial cell proliferation [inference]

regulation of keratinocyte proliferation [inference]

negative regulation of keratinocyte proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of keratinocyte proliferation

regulation of cell differentiation [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of keratinocyte proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

regulation of epidermal cell differentiation [inference]

regulation of keratinocyte differentiation

Displaying **all 5** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
cytosol	ISO	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF GO_REF
side of membrane

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

side of membrane

Displaying 1 entry
GO Term	Evidence Code	Reference
serine-type endopeptidase inhibitor activity

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRSRRLLSAAHLLCLCAVALAAPGSRFLVTAPGIIRPGANVTIGVDLLENSPPQVLVKAQVFKIASNKSRSILEAEGVFHRGHFKTLVLPALPLSSADKIYELHINGQSENEIVFSNRTRLTFESKSISVLIQTDKAFYKPKQEVKFRVLTLCSDLKPYRTSVDIFIKDPKSNVIQQWFSQKGDLGVVSKTFQLSSNPIFGDWSIQVQVNDQQYYQSFQVLEYVLPKFEVTVQTPLYCSLKSKQLNGSVIAKYTYGKPVKGSLSLTFLPLSFWGKKKNITKSFEINGFANFSFDNYEMKKVMNLKPLTDVSEGSYENVDPSFPGPAEIIATVTESLTGISRMASTNVFFKQHDYIIEIFDYTTVLKPSLNFTATVKVSRSDGNQLTPEEIENDLVTVVTQRKNNHPESQRDQEMDYIQTVNYTIPQNGIIKIEFPVMSISGELQLKAYFLDGTSSVTVHSMFTSPSKTYIQLKTRDEYIKVGSPFDLMVSGNRQFKDLSYMVISKGQLVAAGKQSSRTFSLTPEASWAPKACIIAYYIAEDGEIINDILKIPVQLVFENKVKLFWSKPTVKPSDKVSLRISATQSDSLVGIVAVDKSVTLMENSNSITMETMVHELELYNTEYYLGMFMNSFAVFQECGLWVLTDATLIRDSIDEVYDTEEYSERFAEENEANLVDFEDASSVNNVHVRKNFPETWIWLDAYMGSKIYEEFEVTVPDSITSWVASAFVISEDLGFGLTTVPAELQAFQPFFLFLNLPYSVIRGEEFALEVSIVNYLKDTIKVVILIEESDSFDILMTSNDTNGTIYRKTVQVPRDNGVTLVFPIKPTHLGEIPITVTAASPTASDAVTQTIVVKPEGIEKSYSKSVLLDLTDSNVESKQQSMRFSFPPDTVIGSERVQITAIGDILGSSINGLSSLIRMPYGCGEQNMIYFAPNIYILDYLTKQKQLTVNLKEKALSYMRQGYQRELLYQREDGSFSAFGDIDSSGSTWLSAFVLRCFLEADYYIDIDQDVLHRTYTWLNAHKKFNGEFWEPGRVIHSELQGGTKSPVTLTAYIVTSVLGYKKYQPNIDVQDSIKFLEFEFSRGISDNYTLAIISYALSTVGSPKAEEALNLLMQRSEKEGDTQFWLSSGPALSGSWQPRSVDIEIAAYALLAHTLHHVSEGIPVMRWLIQQRNSLGGFVSTQDTVVALKALSEFSALVHKENTDIQLTVTGPGIPRSIHFRIDSQNLFLLHQEELHALDPITVNVSAHGSGFAICQLNVDYNVKGSGSSKRRRSTENQEVFDLDVIVNNEDDISHLNLNVCTSHLGSERTGMVLMEVNLLSGFSASSDSIPLSETLKKVEYDNGKLNLYLDSVNESQFCVNIPTVRDYKVSNIRDGSVSVMDYYEPRRQAVRSYNTQVKLSSCYLSPDTNCKSHTDGATDSLRRSSSLLVFCSVLLYFVQH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	GlyTouCan ID	Source
40		G37818NZ	GlyGen
67	N-linked (GlcNAc...) asparagine		UniProt GlyGen
117	N-linked (GlcNAc...) asparagine		UniProt GlyGen
246	N-linked (GlcNAc...) asparagine	G31852PQ	GlycoProtDB UniProt GlyGen
278	N-linked (GlcNAc...) asparagine		UniProt GlyGen
370	N-linked (GlcNAc...) asparagine	G02815KT	UniProt GlyGen
421	N-linked (GlcNAc...) asparagine		UniProt GlyGen
842			GlyGen
1088	N-linked (GlcNAc...) asparagine	G41247ZX	UniProt GlyGen
1355		G23719VF	GlyGen