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Stabilin-2

Summary

UniProt ID: Q8R4U0
Gene Symbol: Stab2 Feel2 Hare MFEEL-2
Gene ID: 192188
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0006904
GlyGen: Q8R4U0
PubChem: Q8R4U0
The O-GlcNAc Database: Q8R4U0
O-GlcNAcAtlas: Q8R4U0
Re-Glyco: Q8R4U0

Annotation

Keyword: Cell membrane Cytoplasm Disulfide bond EGF-like domain Endocytosis Glycoprotein Hyaluronic acid Laminin EGF-like domain Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
endocytosis	ISS	GO_REF
endocytosis	ISO	GO_REF
receptor-mediated endocytosis	IMP	PMID
receptor-mediated endocytosis	IEA	GO_REF
cell adhesion	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

hyaluronan catabolic process

vesicle-mediated transport [inference]

endocytosis

receptor-mediated endocytosis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to Gram-positive bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium

defense response to Gram-positive bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to Gram-positive bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to Gram-positive bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

receptor-mediated endocytosis

import into cell [inference]

endocytosis

receptor-mediated endocytosis

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GO Term	Evidence Code	Reference
cytosol	ISO	GO_REF
cytosol	IEA	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF GO_REF
external side of plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

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GO Term	Evidence Code	Reference
low-density lipoprotein particle receptor activity	ISO	GO_REF
low-density lipoprotein particle receptor activity	IBA	GO_REF
low-density lipoprotein particle receptor activity	IEA	GO_REF
scavenger receptor activity	ISO	GO_REF
scavenger receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

hyaluronic acid binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

organic acid binding [inference]

carboxylic acid binding [inference]

hyaluronic acid binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding [inference]

low-density lipoprotein particle binding

cargo receptor activity

scavenger receptor activity

lipoprotein particle receptor activity [inference]

low-density lipoprotein particle receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MARSKLLLGKLLPLILIFLGLLVQNACSPTEAPELTKRCDKKSTLTIKTECQSCSVNIAVKCPDGYIKITNGTVGVRDCRYSLKIQSYVLDIPGCRHICRKDYLQPQCCPGHWGPDCMECPGGARAPCGGRGVCDEGMEGTGSCSCRAGFRGTACENCAAEDVFGPNCSAVCSCVHGVCNSGISGDGTCECLSAYRGPRCDKPIPECAALLCPENSRCSPSSKDETKLQCKCLPSYKGDGQTCKPINPCLKNVCHPHASCSYLGPNRHSCVCQKGYQGDGQVCLPVDPCQTSYGNCPTKSTVCRYDGPGQSHCECKEHYRNFVPGVGCSMTDICESKNPCHKNANCSTVSPGQTQCTCQKGYVGDGLNCYGNIMQRLRELNTEPRGMWQGQLTSFISILDRTYAWPLSNLGPFTVLLPSDKGLKGVDVKELLMDKEAARYFVKLHIIAGQMSTEQMYNLDTFYTLTGKSGEIINKDKDNQLKLKLYGSKIVQIIQGNIVASNGLVHILDRAMDKIEPTLESNPQQTIMTMLQPRYGKFRSLLEKTNVGQALEKGGIDEPYTIFVPSNEALSNMTAGVLDYLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTLHIRSMANQIITFNISSKGQILANNVAVDETEVAAKNGRIYTLTGVLIPPSILPILPHRCNETKREMKLGTCVRCFMKNWSKCPTNSEPTAIFTNKCFYGSRAWNLKIGCARYCDVTVEIPRCCKGFFGPDCNPCPGGFMNPCSGNGQCIDGLGGNGTCICEDGFQGSRCQFCSKPNRYGPQCNRTCQCVHGICDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPYMQFCHIHATCEYSNETASCVCNDGYEGDGTLCSKKDPCLGSTSRGGCSPNAECIQASTGTYSCVCQRGWTGNGRDCVEINSCLLPSSGGCHDNATCLYVGPGQNECECKKGFRGNGIDCEPIISCLEQIEKCHPLATCQYTLSGVWSCVCQEGYEGNGVLCYGNVLMELSFLSEAAVFYQWINNASLQSMLSATSNLTVLVPSLQAIKDMDQNEKSFWLSRNNIPALIKYHTLLGTYRVADLQTLPSSHMLATSLQGSFLRLDKADGNITIEGASFVDGDNAATNGVVHIINKVLIPQRGLTGSLPSLLTRLEQMPDYSIFRGYIIHYNLASAIEAADAYTVFVPNNEAIESYIREKKATSLKEDILQYHVVLGEKLLRNDLHNGMHRETMLGFSYLLAFFLHNDQLYVNEAPINYTNVATDKGVIHGLEKVLEIKKNRCDNNDTIIVRGKCGKCSQQTLCPLETKPLSETRKCIYSVYFMGKRSIFIGCQLQCVRTIITSACCAGFFGPQCQACPGKGQNVCSGNGFCLDGVNGTGTCECEQGFNGTACETCTEGKYGIHCDQACSCVHGRCNQGPSGDGSCDCDVGWRGVKCDSEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFQGNGTVCTAINACEISNGGCSAKADCKRTIPGSRVCVCKAGYTGDGIVCLEINPCLENHGGCDRHAECTQTGPNQAVCNCLPKYTGDGKVCTLINVCLTNNGGCSPFAFCNHTEQDQRTCTCKPDYTGDGIVCRGSIHSELPKNPSTSQYFFQLQEHAVQELAGPGPFTVFVPSSDSFNSESKLKVWDKQGLMSQILRYHVVACQQLLLENLKVITSATTLQGEPISISVSQDTVLINKKAKVLSSDIISTNGVIHVIDTLLSPQNLLITPKGASGRVLLNLTTVAANHGYTKFSKLIQDSGLLKVITDPMHTPVTLFWPTDKALQALPQEQQDFLFNEDNKDKLKAYLKFHVIRDTMALASDLPRSASWKTLQGSELSVRCGTGSDVGELFLNGQMCRIIQRRLLFDGGVAYGIDCLLMDPTEGGRCDTFTTFNIPGECGSCFSTPRCPLQSKPKGVRKKCIYNPLPFRRDVEGCQNLCTLVVHVPRCCSGYFMPDCQACPGGPDTPCNNRGMCYDQYKPTGQCQCHTGFNGTACELCLPGRFGPDCQPCGCSEHGQCDEGITGSGQCLCEAGWTGRFCDAPTVVIPVCIPACSMHATCMENNTCVCNLNYEGDGITCTVVDFCKQNNGGCAKVAKCSQKGTQVSCSCQKGYKGDGHSCTEIDPCANGVNGGCHEHATCRMTGPGKQKCECKSHYVGDGRDCEPEQLPLDRCLQDNGQCHPDANCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAKEACAKEAASIATYNQLSYAQKAKYHLCSAGWLESGRVAYPTIYASKKCANIVGIVDYGTRTNKSEMWDVFCYRMKDVNCTCKAGYVGDGFSCNGNLLQVLMSFPSLTNFLTEVLVFSRSSAQGRAFLKHLTDLSISGTLFVPQNSGLPKNKSLSGRDIEHHLTNVNVSFYDDLVNGTVLKTRLGSQLLITSSQDQLHQEARFVDGRAILQWDIIASNGVLHIISEPLKAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSYFRLNQRTTGFRRFESEDDIDALAFGKQQPESITNPLYETSTPAAPEPSCDPFTDSGERELENSDPLGALRS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 32 in total

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Position	Description	Source
71	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt GlyGen
167	N-linked (GlcNAc...) asparagine	UniProt GlyGen
345	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt GlyGen
572	N-linked (GlcNAc...) asparagine	UniProt GlyGen
626	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt GlyGen
673	N-linked (GlcNAc...) asparagine	UniProt GlyGen
691	N-linked (GlcNAc...) asparagine	UniProt GlyGen
768	N-linked (GlcNAc...) asparagine	UniProt GlyGen
796	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt GlyGen
854	N-linked (GlcNAc...) asparagine	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Hyaluronan degradation	Mus musculus
Hyaluronan metabolism	Mus musculus
Scavenging by Class H Receptors	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements