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Citrate synthase, mitochondrial

Summary

UniProt ID: Q8VHF5
Gene Symbol: Cs
Gene ID: 170587
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: Q8VHF5
PubChem: Q8VHF5
The O-GlcNAc Database: Q8VHF5
O-GlcNAcAtlas: Q8VHF5
Re-Glyco: Q8VHF5

Annotation

Keyword: Acetylation Direct protein sequencing Methylation Mitochondrion Phosphoprotein Reference proteome Transferase Transit peptide Tricarboxylic acid cycle Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
carbohydrate metabolic process	ISS	GO_REF
carbohydrate metabolic process	ISO	GO_REF
carbohydrate metabolic process	IBA	GO_REF
acetyl-CoA metabolic process	IDA	PMID
tricarboxylic acid cycle	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

sulfur compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

oxaloacetate metabolic process

tricarboxylic acid metabolic process [inference]

citrate metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

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GO Term	Evidence Code	Reference
mitochondrion	ISO	GO_REF
mitochondrion	IDA	PMID
mitochondrion	IEA	GO_REF
mitochondrial matrix	ISS	GO_REF
mitochondrial matrix	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

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GO Term	Evidence Code	Reference
citrate synthase activity	ISS	GO_REF
citrate synthase activity	ISO	GO_REF
citrate synthase activity	IDA	PMID
citrate synthase activity	IEA	GO_REF GO_REF GO_REF
identical protein binding	ISS	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, acyl groups converted into alkyl on transfer

citrate synthase activity

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MALLTAAARLLGAKNSSCLVLAARHASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLCYTEPQFTELMRLYLTIHSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	PubMed ID	GlyTouCan ID	Source
83	26446791 34502162	G49108TO	GlyGen The O-GlcNAc Database
226	26446791 34502162	G49108TO	GlyGen The O-GlcNAc Database
453	26446791 34502162	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Citric acid cycle (TCA cycle)	Rattus norvegicus
Mitochondrial protein degradation	Rattus norvegicus

Disease

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:6000	congestive heart failure	Alliance of Genome Resources
DOID:7998	hyperthyroidism	Alliance of Genome Resources
DOID:0050852	limb ischemia	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements