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Paxillin
Summary
- UniProt ID
- Q8VI36
- Gene Symbol
- Pxn
- Gene ID
- 19303
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure Acetylation Alternative splicing Cell adhesion Cell junction Cytoskeleton LIM domain Phosphoprotein Reference proteome Repeat
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytoskeleton organization | ||
| transforming growth factor beta receptor signaling pathway | ||
| transforming growth factor beta receptor signaling pathway | ||
| transforming growth factor beta receptor signaling pathway | ||
| integrin-mediated signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| stress fiber | ||
| cytosol | ||
| plasma membrane | ||
| cell-cell junction | ||
| cell-cell junction |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| MAP kinase scaffold activity | ||
| integrin binding | ||
| beta-catenin binding | ||
| vinculin binding | ||
| protein kinase binding |
GO Hierarchy
Sequence
MDDLDALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTVLDPLDQWQPSGSRYAHQQPPSPLPVYSSSAKNSSASNTQDGVGSLCSRAGEEEHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHSPPGFPADEAESSPPLPGALSPLYGIPENNTPLGGKAGPLVKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKMQGLEQRVDGERPWAAGWPPSSRQSSPEGQDEGGFMAQGKTGSSSPPGGLSKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFVKLFC
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| GAB1 signalosome | Mus musculus |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | Mus musculus |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | Mus musculus |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | Mus musculus |
| Smooth Muscle Contraction | Mus musculus |
| VEGFA-VEGFR2 Pathway | Mus musculus |
