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GDP-fucose protein O-fucosyltransferase 2

Summary

UniProt ID: Q8WR51
Gene Symbol: pad-2 CELE_K10G9.3 K10G9.3
Gene ID: 259529
Organism: Caenorhabditis elegans

External Links

GlycoProtDB: GPDB0000916
PubChem: Q8WR51
Re-Glyco: Q8WR51

Annotation

Keyword: 3D-structure Disulfide bond Endoplasmic reticulum Fucose metabolism Glycoprotein Glycosyltransferase Golgi apparatus Reference proteome Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
fucose metabolic process
protein O-linked glycosylation via fucose	ISS	GO_REF
protein O-linked glycosylation via fucose	IDA	PMID
protein O-linked glycosylation via fucose	IEA	GO_REF GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via fucose

Displaying **all 4** entries
GO Term	Evidence Code	Reference
endoplasmic reticulum	ISS	GO_REF
endoplasmic reticulum	IEA	GO_REF
Golgi apparatus	EXP	PMID
Golgi apparatus	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 4** entries
GO Term	Evidence Code	Reference
peptide-O-fucosyltransferase activity	ISS	GO_REF
peptide-O-fucosyltransferase activity	IDA	PMID
peptide-O-fucosyltransferase activity	IBA	GO_REF
peptide-O-fucosyltransferase activity	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

peptide-O-fucosyltransferase activity

catalytic activity, acting on a protein [inference]

peptide-O-fucosyltransferase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MHFFPIQLLVLFFAEKIAFAENSDQTVSRVDSNRYSVAAEKKFLLYDVNFGEGFNLRRDVYMRVANTVRSLRDSGENYILVLPPWGRLHHWKRMEVALSWRLFFDLESLNRFIPVIEFEDFLDENRPIDQVIYLQHYAEGWGTEYVRKFEKRSCLPPAESHYKQVEEFKWKGWFYSYEDVYSRNFQCVSIQGDSGTLKDLLKHSNFSESTSIMVDRAETILHEHYGEVDYWKARRSMRYSNDLVDVADAFRKKYLDSDDKRDKTKLVDDWTKEKPRRTAIGGPYLGIHWRRRDFLYARRAQLPTIPGTAKILQDLCKKLDLQKIYLATDAPDQEVDELKALLNGELEVYRFTDTQKLNDGQIAIIDQYLCAHAAYFIGSYESTFTFRIQEDREIIGFPISTTFNRLCPDTEPTCEQPAKWKIVY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
205	N-linked (GlcNAc...) asparagine	17761667 26854667		GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
O-glycosylation of TSR domain-containing proteins	Caenorhabditis elegans

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:14250	Down syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

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International Collaboration

Acknowledgements