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MIRAGE
Coagulation factor XI
Summary
- UniProt ID
- Q91Y47
- Gene Symbol
- F11
- Gene ID
- 109821
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0007101
- PubChem
- Q91Y47
- Re-Glyco
- Q91Y47
Annotation
- Keyword
- Blood coagulation Disulfide bond Glycoprotein Heparin-binding Reference proteome Repeat Secreted Serine protease Signal Zymogen
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| blood coagulation | ||
| blood coagulation | ||
| regulation of blood coagulation | ||
| plasminogen activation | ||
| plasminogen activation |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| serine-type endopeptidase activity | ||
| heparin binding |
|
|
| serine-type peptidase activity | ||
| identical protein binding | ||
| serine-type aminopeptidase activity |
GO Hierarchy
Sequence
MTSLHQVLYFIFFASVSSECVTKVFKDISFQGGDLSTVFTPSATYCRLVCTHHPRCLLFTFMAESSSDDPTKWFACILKDSVTEILPMVNMTGAISGYSFKQCPQQLSTCSKDVYVNLDMKGMNYNSSVVKNARECQERCTDDAHCQFFTYATGYFPSVDHRKMCLLKYTRTGTPTTITKLNGVVSGFSLKSCGLSNLACIRDIFPNTVLADLNIDSVVAPDAFVCRRICTHHPTCLFFTFFSQAWPKESQRHLCLLKTSESGLPSTRITKSHALSGFSLQHCRHSVPVFCHPSFYNDTDFLGEELDIVDVKGQETCQKTCTNNARCQFFTYYPSHRLCNERNRRGRCYLKLSSNGSPTRILHGRGGISGYSLRLCKMDNVCTTKINPRVVGGAASVHGEWPWQVTLHISQGHLCGGSIIGNQWILTAAHCFSGIETPKKLRVYGGIVNQSEINEGTAFFRVQEMIIHDQYTTAESGYDIALLKLESAMNYTDFQRPICLPSKGDRNAVHTECWVTGWGYTALRGEVQSTLQKAKVPLVSNEECQTRYRRHKITNKMICAGYKEGGKDTCKGDSGGPLSCKYNGVWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQTV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 90 |
|
|
||
| 126 |
|
|
||
| 297 |
|
|
||
| 449 |
|
|
||
| 490 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amplification and propagation of coagulation cascade | Mus musculus |
| FXIIa, PKa activate coagulation factors | Mus musculus |
| Regulation of clotting cascade | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2229 | factor XI deficiency |
