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Acyl-CoA (8-3)-desaturase

Summary

UniProt ID: Q920L1
Gene Symbol: Fads1
Gene ID: 76267
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q920L1
PubChem: Q920L1
Re-Glyco: Q920L1

Annotation

Keyword: Acetylation Electron transport Endoplasmic reticulum Fatty acid biosynthesis Mitochondrion Oxidoreductase Reference proteome Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
lipid metabolic process	IEA	GO_REF
fatty acid biosynthetic process	IMP	PMID PMID
fatty acid biosynthetic process	IEA	GO_REF
unsaturated fatty acid biosynthetic process	ISO	GO_REF GO_REF GO_REF
unsaturated fatty acid biosynthetic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

primary metabolic process [inference]

lipid metabolic process

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonate metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

fatty acid biosynthetic process

unsaturated fatty acid metabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process

olefinic compound metabolic process [inference]

arachidonate metabolic process

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

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GO Term	Evidence Code	Reference
mitochondrion	ISS	GO_REF
mitochondrion	IEA	GO_REF
endoplasmic reticulum membrane	ISS	GO_REF
endoplasmic reticulum membrane	ISO	PMID
endoplasmic reticulum membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
acyl-CoA 6-desaturase activity	ISO	GO_REF
oxidoreductase activity	ISO	GO_REF
oxidoreductase activity	IEA	GO_REF
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	ISO	GO_REF
omega-6 fatty acid desaturase activity	IMP	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

acyl-CoA desaturase activity [inference]

omega-6 fatty acid desaturase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAPDPVPTPGPASAQLRQTRYFTWEEVAQRSGREKERWLVIDRKVYNISDFSRRHPGGSRVISHYAGQDATDPFVAFHINKGLVRKYMNSLLIGELAPEQPSFEPTKNKALTDEFRELRATVERMGLMKANHLFFLVYLLHILLLDVAAWLTLWIFGTSLVPFILCAVLLSTVQAQAGWLQHDFGHLSVFGTSTWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPLFFALGKVLPVELGREKKKHMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVVQRKKWVDLAWMLSFYARIFFTYMPLLGLKGFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNVDWVSTQLQATCNVHQSAFNNWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKYGIKYESKPLLTAFADIVYSLKESGQLWLDAYLHQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites