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Keratin, type II cytoskeletal 5

Summary

UniProt ID: Q922U2
Gene Symbol: Krt2-5 Krt5
Gene ID: 110308
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q922U2
PubChem: Q922U2
RaftProt: Q922U2
O-GlcNAcAtlas: Q922U2
Re-Glyco: Q922U2

Annotation

Keyword: Coiled coil Cytoplasm Direct protein sequencing Intermediate filament Keratin Methylation Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
response to mechanical stimulus	IMP	PMID
regulation of cell migration	IMP	PMID
keratinization	IBA	GO_REF
regulation of protein localization	IMP	PMID
intermediate filament polymerization	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein polymerization [inference]

intermediate filament polymerization

protein-containing complex organization [inference]

intermediate filament polymerization or depolymerization [inference]

intermediate filament polymerization

protein-containing complex assembly [inference]

protein polymerization [inference]

intermediate filament polymerization

supramolecular fiber organization [inference]

intermediate filament organization

multicellular organismal process [inference]

keratinization

response to stimulus [inference]

response to external stimulus [inference]

response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of cellular process [inference]

regulation of cell motility [inference]

regulation of cell migration

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
cornified envelope	IDA	PMID
cytoplasm	ISO	GO_REF
cytoplasm	IDA	PMID PMID
cytoplasm	IEA	GO_REF
mitochondrion	HDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

cornified envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

keratin filament

Displaying **all 2** entries
GO Term	Evidence Code	Reference
structural constituent of skin epidermis	IBA	GO_REF
scaffold protein binding	ISO	GO_REF

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of skin epidermis

binding [inference]

protein binding [inference]

scaffold protein binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSRQSSVSFRSGGSRSFSAASAITPSVSRTSFSSVSRSGGGGGGRISLGGACGAGGYGSRSLYNVGGSKRISYSSGGGSFRNQFGAGGFGFGGGAGSGFGFGGGAGSGFGFGGGAGFGGGYGGAGFPVCPPGGIQEVTVNQNLLTPLNLQIDPTIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTIKQNLDPLFEQYINNLRRQLDGVLGERGRLDSELRNMQDLVEDYKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEARVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRSLDLDSIIAEVKAQYEDIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRSEIDNVKKQCANLQNAIAEAEQRGELALKDARNKLTELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTNSVSSGYGGGSSIGVGSGFGGGLGSGFAGGLGPRFTRGGGGLGLGSGLSVGGSGFSAGSSQGGMSFGSGGGSGSSVKFVSTTSSSRRSFKS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
24				GlyGen
548			G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Formation of the cornified envelope	Mus musculus
Keratinization	Mus musculus
Type I hemidesmosome assembly	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060735	generalized severe epidermolysis bullosa simplex 1A	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements