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Disintegrin and metalloproteinase domain-containing protein 33

Summary

UniProt ID: Q923W9
Gene Symbol: Adam33
Gene ID: 110751
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007174
Re-Glyco: Q923W9

Annotation

Keyword: Alternative splicing Cleavage on pair of basic residues Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Metal-binding Metalloprotease Reference proteome Signal Transmembrane helix Zinc Zymogen

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
regulation of cytokine production	NAS	PMID
proteolysis	NAS	PMID
proteolysis	IBA	GO_REF
proteolysis	IEA	GO_REF
regulation of cell population proliferation	NAS	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

regulation of cell population proliferation

regulation of multicellular organismal process [inference]

regulation of cytokine production

Displaying 1 entry
GO Term	Evidence Code	Reference
membrane	NAS	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	NAS	PMID
metalloendopeptidase activity	IBA	GO_REF
metalloendopeptidase activity	IEA	GO_REF
zinc ion binding	NAS	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGSRCGRPGGSPVLLLLPLLLPSCPLRSARMFPGNAHGELVTPHWILEGRLWLKVTLEEPILKPDSVLVALEAEGQDLLLELEKKHKLLAPGYTETHYRPDGHPVVLSPNHTDHCQYHGRVRGFRESWVVLSTCSGMSGLIVLSSKVSYYLQPRTPGDTKDFPTHEIFRMEQLFTWRGVQRDKNSQYKAGMASLPHVPQSRVRREARRSPRYLELYIVADHTLFLLQHQNLNHTRQRLLEVANCVDQILRTLDIQLVLTGLEVWTEQDLSRITQDANETLWAFLQWRRGVWARRPHDSTQLLTGRTFQGTTVGLAPVEGICRAESSGGVSTDHSELPIGTAATMAHEIGHSLGLHHDPEGCCVQADAEQGGCVMEAATGHPFPRVFSACSRRQLRTFFRKGGGPCLSNTSAPGLLVLPSRCGNGFLEAGEECDCGSGQKCPDPCCFAHNCSLRAGAQCAHGDCCARCLLKSAGTPCRPAATDCDLPEFCTGTSPYCPADVYLLDGSPCAEGRGYCLDGWCPTLEQQCQQLWGPGSKPAPEPCFQQMNSMGNSQGNCGQDHKGSFLPCAQRDALCGKLLCQGGEPNPLVPHIVTMDSTILLEGREVVCRGAFVLPDSHLDQLDLGLVEPGTGCGPRMVCQDRHCQNATSQELERCLTACHNGGVCNSNRNCHCAAGWAPPFCDKPGLGGSVDSGPAQSANRDAFPLAMLLSFLLPLLPGAGLAWCYYQLPTFCHRRGLCCRRDPLWNRDIPLGSVHPVEFGSIITGEPSPPPPWTSCQQRSHPPSLDLLSDPANSELT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
110	N-linked (GlcNAc...) asparagine	UniProt
232	N-linked (GlcNAc...) asparagine	UniProt
277	N-linked (GlcNAc...) asparagine	UniProt
408	N-linked (GlcNAc...) asparagine	UniProt
449	N-linked (GlcNAc...) asparagine	UniProt
645	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt