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Exostosin-2

Summary

UniProt ID

Q93063

Gene Symbol

EXT2

Gene ID

2132

Organism

Homo sapiens (human)

External Links

GlyGen: Q93063
PubChem: Q93063
The Human Metabolome Database: HMDBP01702
Re-Glyco: Q93063

Annotation

Keyword

3D-structure
Alternative splicing
Disease variant
Disulfide bond
Endoplasmic reticulum
Epilepsy
Glycoprotein
Glycosyltransferase
Golgi apparatus
Hereditary multiple exostoses
Intellectual disability
Manganese
Metal-binding
Reference proteome
Secreted
Signal-anchor
Transmembrane helix
Tumor suppressor

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
catalytic complex
membrane
Golgi membrane
endoplasmic reticulum
Golgi apparatus
UDP-N-acetylglucosamine transferase complex
extracellular exosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 19 in total

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2

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GO Term
gene expression
polysaccharide biosynthetic process
ossification
mesoderm formation
glycosaminoglycan biosynthetic process
protein N-linked glycosylation
regulation of blood pressure
heparin biosynthetic process
fluid transport
multicellular organismal-level water homeostasis

Displaying **all 7** entries
GO Term
glucuronosyltransferase activity
glycosyltransferase activity
metal ion binding
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
protein heterodimerization activity
heparan sulfate N-acetylglucosaminyltransferase activity

Annotation information from UniProt.

Sequence

MCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites