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Phosphoinositide-3-kinase-interacting protein 1

Summary

UniProt ID: Q96FE7
Gene Symbol: PIK3IP1 HGFL
Gene ID: 113791
Organism: Homo sapiens (human)

External Links

GlyConnect

Phosphoinositide-3-kinase-interacting protein 1

GlyGen

Q96FE7

Re-Glyco

Q96FE7

Annotation

Keyword: Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Kringle Proteomics identification Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	Reference
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	PMID
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IBA	GO_REF

GO Hierarchy

biological process

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
endopeptidase activity	IBA	GO_REF
signaling receptor binding	IBA	GO_REF
phosphatidylinositol 3-kinase inhibitor activity	ISS	GO_REF
phosphatidylinositol 3-kinase inhibitor activity	IPI	PMID
phosphatidylinositol 3-kinase inhibitor activity	IEA	GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

binding [inference]

protein binding [inference]

signaling receptor binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

kinase regulator activity [inference]

phosphatidylinositol 3-kinase regulator activity [inference]

phosphatidylinositol 3-kinase inhibitor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLLAWVQAFLVSNMLLAEAYGSGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCEDLRCPETTSQALPAFTTEIQEASEGPGADEVQVFAPANALPARSEAAAVQPVIGISQRVRMNSKEKKDLGTLGYVLGITMMVIIIAIGAGIILGYSYKRGKDLKEQHDQKVCEREMQRITLPLSAFTNPTCEIVDEKTVVVHTSQTPVDPQEGTTPLMGQAGTPGA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
38		30237853	G81006GJ G74722FL G29931IJ	GlyGen GlyConnect
39	O-linked (GalNAc...) serine	22171320 30237853	G27945LI G74722FL G29931IJ G43417UB	UniProt GlyGen GlyConnect
58		30237853		GlyConnect
66	N-linked (GlcNAc...) (complex) asparagine	22171320 23090970 24190977 30237853 37074911	G15169WU G61806WR G11629QQ G77669RF G86234IN G06330RB G51413EV G22310AV G48414YA G25418HZ G84452RH G23863VK G83555HU	UniProt GlyGen GlyConnect
72		24190977		GlyGen
120		30459171	G43417UB	GlyGen
141		25813380	G57321FI	GlyGen
260				GlyGen