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MIRAGE
Solute carrier family 22 member 12
Summary
- UniProt ID
- Q96S37
- Gene Symbol
- SLC22A12 OATL4 UNQ6453/PRO34004 URAT1
- Gene ID
- 116085
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure Alternative splicing Cell membrane Disease variant Glycoprotein Ion transport Phosphoprotein Proteomics identification Reference proteome Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| response to xenobiotic stimulus | ||
| organic anion transport |
|
|
| urate transport | ||
| urate transport | ||
| urate transport |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| membrane | ||
| apical plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| urate transmembrane transporter activity | ||
| urate transmembrane transporter activity | ||
| PDZ domain binding |
GO Hierarchy
Sequence
MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) | Homo sapiens |
| Organic anion transport by SLC22 transporters | Homo sapiens |
