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Structural maintenance of chromosomes protein 6

Summary

UniProt ID

Q96SB8

Gene Symbol

SMC6
SMC6L1

Gene ID

79677

Organism

Homo sapiens (human)

External Links

GlyGen: Q96SB8
PubChem: Q96SB8
The O-GlcNAc Database: Q96SB8
O-GlcNAcAtlas: Q96SB8
Re-Glyco: Q96SB8

Annotation

Keyword

ATP-binding
Alternative splicing
Coiled coil
DNA recombination
DNA repair
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Telomere
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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2

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GO Term
nucleoplasm
chromosome, centromeric region
chromosome, telomeric region
PML body
site of double-strand break
nuclear speck
mitotic spindle pole
sex chromosome
Smc5-Smc6 complex
interchromatin granule

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
positive regulation of chromosome segregation
DNA damage response
telomere maintenance via recombination
protein sumoylation
regulation of telomere maintenance
cellular senescence
negative regulation by host of viral genome replication
chromatin looping
double-strand break repair via homologous recombination

Displaying **all 6** entries
GO Term
damaged DNA binding
ATP binding
ATP hydrolysis activity
ubiquitin protein ligase binding
single-stranded DNA binding
DNA secondary structure binding

Annotation information from UniProt.

Sequence

MAKRKEENFSSPKNAKRPRQEELEDFDKDGDEDECKGTTLTAAEVGIIESIHLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDGQNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKLKSATGSVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQIHQGEERLTELKRQCVEKEERFQSIAGLSTMKTNLESLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVRLNEAEQKYKDIQDKLEKISEETNARAPECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDEQLCKRIEELKKSTDQSLEPERLERQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVKHALSYNQRQLKELKDSKTDRLKRFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKRFYLPGTSRPPIIVSEFRNEIYDVRHRAAYHPDFPTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSENTRPKFLSRDVDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVEKSASILDKEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDSKVRTLKKFIKLLGEIMEHRFKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDDQR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites