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Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

Summary

UniProt ID: Q99NA5
Gene Symbol: Idh3a
Gene ID: 114096
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: Q99NA5
PubChem: Q99NA5
The O-GlcNAc Database: Q99NA5
O-GlcNAcAtlas: Q99NA5
Re-Glyco: Q99NA5

Annotation

Keyword: Acetylation Direct protein sequencing Magnesium Manganese Metal-binding Mitochondrion NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
tricarboxylic acid cycle	ISO	GO_REF
tricarboxylic acid cycle	IBA	GO_REF
tricarboxylic acid cycle	IEA	GO_REF
isocitrate metabolic process

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

tricarboxylic acid cycle

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

isocitrate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

isocitrate metabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
mitochondrion	ISO	GO_REF
mitochondrion	NAS	PMID
mitochondrion	IBA	GO_REF
mitochondrion	IEA	GO_REF
mitochondrial matrix	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

tricarboxylic acid cycle heteromeric enzyme complex [inference]

isocitrate dehydrogenase complex (NAD+)

oxidoreductase complex [inference]

isocitrate dehydrogenase complex (NAD+)

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
magnesium ion binding	ISS	GO_REF
magnesium ion binding	ISO	GO_REF
magnesium ion binding	IEA	GO_REF
isocitrate dehydrogenase (NAD+) activity	ISS	GO_REF
isocitrate dehydrogenase (NAD+) activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

isocitrate dehydrogenase [NAD(P)+] activity [inference]

isocitrate dehydrogenase (NAD+) activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAGSAWVSKVSRLLGAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTQSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNSKCSDFTEEICRRVKDLD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites