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ATP-binding cassette sub-family G member 5

Summary

UniProt ID: Q99PE8
Gene Symbol: Abcg5
Gene ID: 27409
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q99PE8
PubChem: Q99PE8
Re-Glyco: Q99PE8

Annotation

Keyword: ATP-binding Cell membrane Disease variant Glycoprotein Lipid transport Magnesium Metal-binding Palmitate Reference proteome Translocase Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
response to nutrient	IEA	GO_REF
response to xenobiotic stimulus	IEA	GO_REF
response to ionizing radiation	IEA	GO_REF
negative regulation of intestinal phytosterol absorption	ISO	GO_REF
negative regulation of intestinal phytosterol absorption	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

intestinal absorption [inference]

intestinal lipid absorption [inference]

intestinal cholesterol absorption

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

acylglycerol homeostasis [inference]

triglyceride homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation

response to activity [inference]

response to muscle activity

response to nutrient levels [inference]

response to nutrient

response to chemical [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport [inference]

sterol transport

cholesterol transport [inference]

cholesterol efflux

organic hydroxy compound transport [inference]

sterol transport

cholesterol transport [inference]

cholesterol efflux

transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of intestinal absorption [inference]

negative regulation of intestinal lipid absorption [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

negative regulation of digestive system process [inference]

negative regulation of intestinal absorption [inference]

negative regulation of intestinal lipid absorption [inference]

regulation of intestinal absorption [inference]

negative regulation of intestinal absorption [inference]

negative regulation of intestinal lipid absorption [inference]

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption [inference]

negative regulation of intestinal cholesterol absorption

negative regulation of intestinal lipid absorption [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of digestive system process [inference]

negative regulation of intestinal absorption [inference]

negative regulation of intestinal lipid absorption [inference]

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
plasma membrane	EXP	PMID
plasma membrane	IDA	PMID
plasma membrane	IEA	GO_REF
membrane	IDA	PMID
membrane	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

ATP-binding cassette (ABC) transporter complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

ATP-binding cassette (ABC) transporter complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

ATP-binding cassette (ABC) transporter complex

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

apical part of cell

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
ATP binding	ISO	GO_REF
ATP binding	IEA	GO_REF GO_REF
ATP hydrolysis activity	ISO	GO_REF
ATP hydrolysis activity	IEA	GO_REF GO_REF
ATPase-coupled transmembrane transporter activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

binding [inference]

protein binding [inference]

protein dimerization activity [inference]

protein heterodimerization activity

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular carrier activity [inference]

lipid carrier activity [inference]

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGELPFLSPEGARGPHINRGSLSSLEQGSVTGTEARHSLGVLHVSYSVSNRVGPWWNIKSCQQKWDRQILKDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTLEGEVFVNGCELRRDQFQDCFSYVLQSDVFLSSLTVRETLRYTAMLALCRSSADFYNKKVEAVMTELSLSHVADQMIGSYNFGGISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLLLAELARRDRIVIVTIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDLTSVDTQSREREIETYKRVQMLECAFKESDIYHKILENIERARYLKTLPTVPFKTKDPPGMFGKLGVLLRRVTRNLMRNKQAVIMRLVQNLIMGLFLIFYLLRVQNNTLKGAVQDRVGLLYQLVGATPYTGMLNAVNLFPMLRAVSDQESQDGLYHKWQMLLAYVLHVLPFSVIATVIFSSVCYWTLGLYPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSIVALLSISGLLIGSGFIRNIQEMPIPLKILGYFTFQKYCCEILVVNEFYGLNFTCGGSNTSMLNHPMCAITQGVQFIEKTCPGATSRFTANFLILYGFIPALVILGIVIFKVRDYLISR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	Source
410	N-linked (GlcNAc...) asparagine		UniProt GlyGen
585	N-linked (GlcNAc...) asparagine	15054092	UniProt GlyGen
592	N-linked (GlcNAc...) asparagine	15054092	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
ABC transporters in lipid homeostasis	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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