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MIRAGE
Sodium/iodide cotransporter

Summary
UniProt ID
Q99PN0
Gene Symbol
Slc5a5 Nis
Gene ID
Organism
Mus musculus (house mouse)
PubChem
Q99PN0
Re-Glyco
Q99PN0
Annotation
Keyword
Cell membrane Cytoplasm Glycoprotein Metal-binding Phosphoprotein Reference proteome Sodium transport Symport Transmembrane helix
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code Reference
thyroid hormone generation
sodium ion transport
sodium ion transport
iodide transport
iodide transport
GO Hierarchy
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code Reference
sodium:iodide symporter activity
sodium:iodide symporter activity
sodium:iodide symporter activity
sodium:iodide symporter activity
iodide transmembrane transporter activity
GO Hierarchy
Gene Ontology information from UniProt.
Annotation information from UniProt.
Sequence
MEGAEAGARATFGPWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCVGQLLNSLLTALLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVMLMGGPWNVLSLAQNHSRINLMDFDPDPRSRYTFWTFVVGGSLVWLSMYGVNQAQVQRYVACHTERKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRIAAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPSLAPRKLVFISKGLSFIYGSTCLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLTAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNASVLPSPPGAANTSRGIPSSGMDSGRPAFADTFYAVSYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTTTLEDSLVKGPEDIPAATKKPPGFRPEAETHPLYLGHDVETNL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
485
  • N-linked (GlcNAc...) asparagine
497
  • N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
SLC-mediated transport of inorganic anions Mus musculus
Thyroxine biosynthesis Mus musculus
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026