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Protein tweety homolog 2

Summary

UniProt ID: Q9BSA4
Gene Symbol: C17orf29 TTYH2
Gene ID: 94015
Organism: Homo sapiens (human)

External Links

GlyGen: Q9BSA4
The Human Metabolome Database: HMDBP08229
Re-Glyco: Q9BSA4

Annotation

Keyword: 3D-structure Alternative splicing Calcium Cell membrane Chloride channel Disulfide bond Glycoprotein Metal-binding Phosphoprotein Proteomics identification Reference proteome Transmembrane helix Ubl conjugation

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	Reference
L-glutamate transmembrane transport	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

nitrogen compound transport [inference]

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

Displaying **all 4** entries
GO Term	Evidence Code	Reference
plasma membrane	IDA	PMID PMID PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF
chloride channel complex

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
intracellularly calcium-gated chloride channel activity	IBA	GO_REF
calcium ion binding	ISS	GO_REF
calcium ion binding	IEA	GO_REF
volume-sensitive chloride channel activity	IBA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity [inference]

volume-sensitive chloride channel activity

chloride channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity [inference]

volume-sensitive chloride channel activity

chloride channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity [inference]

volume-sensitive chloride channel activity

chloride channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

intracellularly calcium-gated channel activity [inference]

intracellularly calcium-gated chloride channel activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MQAARVDYIAPWWVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNLIFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQLMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGSVVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKCLLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYCSQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	Source
31	N-linked (GlcNAc...) asparagine	18260827 34385445	UniProt GlyGen
129	N-linked (GlcNAc) asparagine	18260827 34385445	UniProt GlyGen
283	N-linked (GlcNAc...) asparagine	18260827 34385445	UniProt GlyGen
352	N-linked (GlcNAc) asparagine	18260827 34385445	UniProt GlyGen