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N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

Summary

UniProt ID: Q9CWS0
Gene Symbol: Ddah1
Gene ID: 69219
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9CWS0
PubChem: Q9CWS0
The O-GlcNAc Database: Q9CWS0
O-GlcNAcAtlas: Q9CWS0
Re-Glyco: Q9CWS0

Annotation

Keyword: Acetylation Direct protein sequencing Hydrolase Metal-binding Phosphoprotein Reference proteome S-nitrosylation Zinc

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
citrulline metabolic process
regulation of systemic arterial blood pressure	IMP	PMID
arginine metabolic process	ISO	GO_REF
arginine metabolic process	IBA	GO_REF
L-arginine catabolic process	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

amino acid catabolic process [inference]

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-arginine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

biosynthetic process [inference]

nitric oxide biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-arginine catabolic process

non-proteinogenic amino acid metabolic process [inference]

citrulline metabolic process

alpha-amino acid metabolic process [inference]

citrulline metabolic process

arginine metabolic process

L-arginine catabolic process

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-arginine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-arginine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

proteinogenic amino acid metabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-arginine catabolic process

non-proteinogenic amino acid metabolic process [inference]

citrulline metabolic process

alpha-amino acid metabolic process [inference]

citrulline metabolic process

arginine metabolic process

L-arginine catabolic process

L-amino acid metabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

proteinogenic amino acid catabolic process [inference]

L-arginine catabolic process

alpha-amino acid catabolic process [inference]

L-amino acid catabolic process [inference]

L-arginine catabolic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process [inference]

nitric oxide biosynthetic process

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of response to stimulus [inference]

negative regulation of cellular response to hypoxia

regulation of response to stimulus [inference]

negative regulation of response to stimulus [inference]

negative regulation of cellular response to hypoxia

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of cellular response to hypoxia [inference]

negative regulation of cellular response to hypoxia

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

negative regulation of cellular process [inference]

regulation of cellular response to stress [inference]

regulation of cellular response to hypoxia [inference]

negative regulation of cellular response to hypoxia

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure

regulation of vascular permeability [inference]

negative regulation of vascular permeability

Displaying 1 entry
GO Term	Evidence Code	Reference
mitochondrion	HDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
zinc ion binding	ISO	PMID
dimethylargininase activity	ISS	GO_REF
dimethylargininase activity	ISO	PMID PMID GO_REF GO_REF
dimethylargininase activity	EXP	PMID
dimethylargininase activity	IMP	PMID PMID PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [inference]

dimethylargininase activity

binding [inference]

amino acid binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAGLGHPSAFGRATHAVVRAPPESLCRHALRRSQGEEVDFARAERQHELYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADSLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDMAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHLLIPVSNSEMEKVDGLLTCCSVFINKKIDS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites