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MIRAGE

ATP-dependent (S)-NAD(P)H-hydrate dehydratase

Summary

UniProt ID: Q9CZ42
Gene Symbol: Naxd CARKD Carkd
Gene ID: 69225
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0007320

GlyConnect

ATP-dependent (S)-NAD(P)H-hydrate dehydratase

GlyGen

Q9CZ42

PubChem

Q9CZ42

RaftProt

Q9CZ42

Re-Glyco

Q9CZ42

Annotation

Keyword: ATP-binding Acetylation Alternative splicing Lyase Mitochondrion NAD NADP Phosphoprotein Reference proteome Transit peptide

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
nicotinamide nucleotide metabolic process	IEA	GO_REF
metabolite repair	ISO	GO_REF
metabolite repair	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process

metabolite repair

Displaying **all 5** entries
GO Term	Evidence Code	Reference
mitochondrion	IDA	PMID
mitochondrion	IEA	GO_REF GO_REF
mitochondrion	HDA	PMID
endoplasmic reticulum	IDA	PMID
cytosol	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 4** entries
GO Term	Evidence Code	Reference
ATP binding
ATP-dependent NAD(P)H-hydrate dehydratase activity	ISO	GO_REF GO_REF
ATP-dependent NAD(P)H-hydrate dehydratase activity	EXP	PMID
ATP-dependent NAD(P)H-hydrate dehydratase activity	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

ATP-dependent NAD(P)H-hydrate dehydratase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAVHACGAAAAVVALLSAAIALQWSPLYAVLQRALSLHTAHATKDMENLFQLVRNIVPALTSKKHKGQDGRIGIVGGCQEYTGAPYFAGISALKVGADLTHVFCAREAAPVIKSYSPELIVHPVLDSSNAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKARDIPVVIDADGLWLVAQQPALIHSYHKAILTPNHVEFSRLWEAVLSSPMDSNDLKGSTLKLSQALGNITVVQKGEQDLISNGQQVLVCNQEGSSRRCGGQGDLLSGSLGVMVHWALRAGPEKTNGSSPLLVAAWGACTLTRECNRQAFQKYGRSTTTTDMITEVGTAFSRLFTT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
236		30899004	G80920RR G39188ZX G06110VR	GlycoProtDB GlyGen GlyConnect
293				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Nicotinate metabolism	Mus musculus

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026