GlyCosmos Portal

Protein tweety homolog 1

Summary

UniProt ID: Q9D3A9
Gene Symbol: Ttyh1
Gene ID: 57776
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007365
PubChem: Q9D3A9
Re-Glyco: Q9D3A9

Annotation

Keyword: Alternative splicing Cell adhesion Cell membrane Chloride channel Disulfide bond Glycoprotein Metal-binding Phosphoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
mitotic cell cycle	IMP	PMID
cell morphogenesis	IMP	PMID
chloride transport	ISO	GO_REF
chloride transport	IEA	GO_REF
Notch signaling pathway	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell cycle [inference]

mitotic cell cycle

cell adhesion [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cell population proliferation [inference]

stem cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

filopodium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

filopodium assembly

plasma membrane bounded cell projection organization [inference]

plasma membrane bounded cell projection assembly [inference]

filopodium assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

inorganic anion transport [inference]

chloride transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

nitrogen compound transport [inference]

L-amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	EXP	PMID
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

chloride channel complex

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

smooth endoplasmic reticulum membrane

bounding membrane of organelle [inference]

smooth endoplasmic reticulum membrane

plasma membrane region [inference]

cell projection membrane [inference]

filopodium membrane

cell junction [inference]

synapse

filopodium tip

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
intracellularly calcium-gated chloride channel activity	IBA	GO_REF
calcium ion binding	IDA	PMID
volume-sensitive chloride channel activity	ISO	GO_REF
volume-sensitive chloride channel activity	IDA	PMID
volume-sensitive chloride channel activity	IBA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity [inference]

volume-sensitive chloride channel activity

chloride channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity [inference]

volume-sensitive chloride channel activity

chloride channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

volume-sensitive anion channel activity [inference]

volume-sensitive chloride channel activity

chloride channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

intracellularly calcium-gated channel activity [inference]

intracellularly calcium-gated chloride channel activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPHGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDDVVLETVERLGEAVKTELTTLEEVLSVRMELVAATRGARRQAEAAAQYLQGLAFWQGVSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGLSSDILSYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREAIPQFSAAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
130	N-linked (GlcNAc...) asparagine	UniProt
284	N-linked (GlcNAc...) asparagine	UniProt
355	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Stimuli-sensing channels	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements