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Ubiquitin-like modifier-activating enzyme ATG7
Summary
- UniProt ID
- Q9D906
- Gene Symbol
- Apg7l Atg7
- Gene ID
- 74244
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Acetylation Autophagy Biological rhythms Cytoplasm Isopeptide bond Phosphoprotein Protein transport Reference proteome Ubl conjugation Ubl conjugation pathway
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| autophagosome assembly | ||
| autophagosome assembly | ||
| autophagosome assembly | ||
| autophagosome assembly | ||
| autophagy of mitochondrion |
GO Hierarchy
- rhythmic process
- regulation of circadian rhythm
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| Atg12 activating enzyme activity | ||
| Atg12 activating enzyme activity | ||
| Atg12 activating enzyme activity | ||
| Atg12 activating enzyme activity | ||
| Atg12 activating enzyme activity |
GO Hierarchy
Sequence
MGDPGLAKLQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTPAHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKYHFYYWFCCPALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALPYFLFKYDDDTVLVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRNFLVLAAHRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHLVAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEGGYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDEETV
Glycosylation Sites
G70101JE
G64527OM
G41954QW
G76393RH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen processing: Ubiquitination & Proteasome degradation | Mus musculus |
| Macroautophagy | Mus musculus |
| Neutrophil degranulation | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:9074 | systemic lupus erythematosus | |
| DOID:14330 | Parkinson's disease |
