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ATP-binding cassette sub-family G member 8
Summary
- UniProt ID
- Q9DBM0
- Gene Symbol
-
- Abcg8
- Gene ID
- 67470
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Glycoprotein
- Lipid transport
- Magnesium
- Metal-binding
- Reference proteome
- Translocase
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| ATP-binding cassette (ABC) transporter complex |
| plasma membrane |
| receptor complex |
| apical plasma membrane |
| GO Term |
|---|
| sterol transport |
| response to nutrient |
| response to xenobiotic stimulus |
| response to muscle activity |
| phospholipid transport |
| cholesterol efflux |
| cholesterol homeostasis |
| triglyceride homeostasis |
| intestinal cholesterol absorption |
| sterol homeostasis |
| GO Term |
|---|
| metal ion binding |
| ATP binding |
| ATP hydrolysis activity |
| protein heterodimerization activity |
| cholesterol transfer activity |
| ABC-type transporter activity |
Sequence
MAEKTKEETQLWNGTVLQDASQGLQDSLFSSESDNSLYFTYSGQSNTLEVRDLTYQVDIASQVPWFEQLAQFKIPWRSHSSQDSCELGIRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQIWINGQPSTPQLVRKCVAHVRQHDQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDLTSIDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLWKAEAKELNTSTHTVSLTLTQDTDCGTAVELPGMIEQFSTLIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGAKQLSFMDTAALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNLRPVPELFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSSFFCNALYNSFYLTAGFMINLDNLWIVPAWISKLSFLRWCFSGLMQIQFNGHLYTTQIGNFTFSILGDTMISAMDLNSHPLYAIYLIVIGISYGFLFLYYLSLKLIKQKSIQDW
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABC transporters in lipid homeostasis | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090019 | sitosterolemia 1 |
