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MIRAGE

Ectonucleotide pyrophosphatase/phosphodiesterase family member 5

Summary

UniProt ID: Q9EQG7
Gene Symbol: Enpp5
Gene ID: 83965
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0007506

GlyConnect

Ectonucleotide pyrophosphatase/phosphodiesterase family member 5

GlyGen

Q9EQG7

PubChem

Q9EQG7

Re-Glyco

Q9EQG7

Annotation

Keyword: 3D-structure Glycoprotein Hydrolase Metal-binding Reference proteome Secreted Signal Transmembrane helix Zinc

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
cell communication	ISO	GO_REF
cell communication	IEA	GO_REF
nucleotide catabolic process	ISA	PMID

GO Hierarchy

biological process

cellular process [inference]

cell communication

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

nucleotide catabolic process

nucleoside phosphate catabolic process [inference]

nucleotide catabolic process

Displaying **all 4** entries
GO Term	Evidence Code	Reference
extracellular region	IEA	GO_REF
plasma membrane	ISA	PMID
plasma membrane	ISO	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	Reference
NAD+ diphosphatase activity	ISO	GO_REF
NAD+ diphosphatase activity	EXP	PMID
NAD+ diphosphatase activity	IEA	GO_REF GO_REF
dinucleotide phosphatase activity	ISA	PMID
zinc ion binding	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

dinucleotide phosphatase activity

NAD+ diphosphatase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MIPEFLLASCTLATLCHSAPFSLQPEEQKVLVVSFDGFRWDYLYKVPTPHFHYIMKNGVHVNQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPDDTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHYTLIDHSPVAAILPKEGKFDEVYDALAGAHPNLTVYKKEEIPERWHYKHNDRVQPIVAVADEGWYILQNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLLCHLLNLTALPHNGSFWNVQDLLSSATPKPIPYTQSTTLLLGSDKPGEDEQEESYPYYIGVSLGSIIAMVFFVVLIKHLIRSQVHTLQYRQVEVAQPLLQA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
101	N-linked (GlcNAc...) asparagine	30899004	G14260UH G64527OM G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
158	N-linked (GlcNAc...) asparagine	30899004	G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
292	N-linked (GlcNAc...) asparagine	30899004	G70101JE G80920RR G14260UH G64527OM G14669DU	GlycoProtDB UniProt GlyGen GlyConnect
329	N-linked (GlcNAc...) asparagine	30899004	G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
343				GlyGen
362	N-linked (GlcNAc...) asparagine	30899004	G74724QE G22355FZ	UniProt GlyGen GlyConnect
369	N-linked (GlcNAc...) asparagine			UniProt GlyGen
382	N-linked (GlcNAc...) asparagine			UniProt GlyGen
389	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026