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Exostosin-like 2

Summary

UniProt ID: Q9ES89
Gene Symbol: Extl2 Extr2
Gene ID: 58193
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007526
RaftProt: Q9ES89
Re-Glyco: Q9ES89

Annotation

Keyword: 3D-structure Disulfide bond Endoplasmic reticulum Glycoprotein Glycosyltransferase Manganese Metal-binding Reference proteome Signal-anchor Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
N-acetylglucosamine metabolic process	ISO	GO_REF
N-acetylglucosamine metabolic process	IMP	PMID
N-acetylglucosamine metabolic process	IEA	GO_REF GO_REF
UDP-N-acetylgalactosamine metabolic process	ISO	GO_REF
UDP-N-acetylgalactosamine metabolic process	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	Reference
nucleoplasm	ISO	GO_REF
endoplasmic reticulum	ISO	GO_REF
endoplasmic reticulum	IEA	GO_REF
endoplasmic reticulum membrane	IEA	GO_REF
cytosol	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	ISO	GO_REF
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	EXP	PMID
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	IEA	GO_REF GO_REF GO_REF
glycosaminoglycan binding	IMP	PMID
manganese ion binding	IMP	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

acetylgalactosaminyltransferase activity [inference]

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

acetylgalactosaminyltransferase activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MMRGCHICKLPGRVMGIRVLRFSLVVILVLLLVAGALTNLLPNIKEDKMLTLRREIKSPSKSALDSFTLIMQTYNRTDLLLRLLNHYQAVPSLHKVIVVWNNVGEKGPEELWNSLGPHPIPVIFKPQTANKMRNRLQVFPEVETNAVLMVDDDTLISAQDLVFAFSIWQQFPDQIIGFVPRKHVSTSSGIYSYGGFELQTPGPGNGDQYSMVLIGASFFNSKYLELFQKQPAAVHALIDETQNCDDIAMNFLVTRHTGKPSGIFVKPINMVNLEKETNGYSGMWHRAEHFLQRSYCINKLVNIYDGMPLKYSNIMISQFGFPYANHKSKM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
75	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
HS-GAG biosynthesis	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements