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Histone acetyltransferase KAT8

Summary

UniProt ID

Q9H7Z6

Gene Symbol

KAT8
MOF
MYST1
PP7073

Gene ID

84148

Organism

Homo sapiens (human)

External Links

GlyGen: Q9H7Z6
PubChem: Q9H7Z6
The Human Metabolome Database: HMDBP09985
Re-Glyco: Q9H7Z6

Annotation

Keyword

3D-structure
Acetylation
Activator
Acyltransferase
Alternative splicing
Chromatin regulator
Chromosome
Disease variant
Intellectual disability
Mitochondrion
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Zinc-finger

Gene Ontology (GO)

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GO Term
MLL1 complex
histone acetyltransferase complex
kinetochore
nuclear matrix
NSL complex
NuA4 histone acetyltransferase complex
MSL complex
chromatin
nucleus
chromosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
negative regulation of type I interferon production
post-embryonic hemopoiesis
transcription initiation-coupled chromatin remodeling
regulation of mRNA processing
positive regulation of transcription initiation by RNA polymerase II
regulation of mitochondrial transcription
positive regulation of skeletal muscle satellite cell differentiation
neurogenesis
myeloid cell differentiation
oogenesis

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GO Term
metal ion binding
histone H3K14 acetyltransferase activity
histone H3K23 acetyltransferase activity
histone H4K5 acetyltransferase activity
histone H4K8 acetyltransferase activity
histone H4K12 acetyltransferase activity
histone H3K4 acetyltransferase activity
transcription coregulator activity
enzyme binding
histone H4K16 acetyltransferase activity

Annotation information from UniProt.

Sequence

MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites