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Repository for lectin-assisted multimodality data
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MIRAGE
Macrophage colony-stimulating factor 1 receptor
Summary
- UniProt ID
- Q9I8N6
- Gene Symbol
- csf1r fms
- Gene ID
- 64274
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
- ATP-binding Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Inflammatory response Innate immunity Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| immune response in brain or nervous system | ||
| lipid metabolic process | ||
| inflammatory response |
|
|
| cell surface receptor protein tyrosine kinase signaling pathway | ||
| cell surface receptor protein tyrosine kinase signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| signaling receptor complex | ||
| CSF1-CSF1R complex |
| GO Term | Evidence Code | Reference |
|---|---|---|
| macrophage colony-stimulating factor receptor activity | ||
| ATP binding | ||
| growth factor binding | ||
| cytokine binding |
GO Hierarchy
Sequence
MFFALLFLIGILLGQVQGWSEPRIRLSSGALAGTDVILESGSPLQLVCEGDGPVTFLPRLAKHKRYISKEVGKIRSFRVEKTTVDFTGTYKCVYMNGNDSNLSSSVHVFVRDSRVLFVSPSTSLRYVRKEGEDLLLPCLLTDPEATDFTFRMDNGSAAPYGMNITYDPRKGVLIRNVHPGFNADYICCARIGGAEKVSKIFSINIIQRLRFPPYVYLKRNEYVKLVGERLQISCTTNNPNFYYNVTWTHSSRMLPKAEEKSTMEGDRLAIESILTIPSVQLSHTGNITCTGQNEAGANSSTTQLLVVEEPYIRLSPKLSSKLTHRGLSIEVSEGDDVDLGVLIEAYPPLTSHKWETPTSHNASLPENRFFNHNDRYEALLLLKRLNFEEIGQYTLNVKNSMKSASITFDIKMYTKPVARVKWENVTTLSCRSYGYPAPSILWYQCTGIRTTCPENTTDLQPIQTQTVEFQKESFGAVGVESVLTVGPNRRMTVVCVAFNLVGQGSDTFSMEVSDQIFTSAMCGSTVAMVVLGLLLIFMIYKYKQKPRYEIRWKIIEATNGNNYTFIDPTQLPYNEKWEFPRDKLKLGKTLGAGAFGKVVEATAYGLGKEDNITRVAVKMLKASAHPDEREALMSELKILSHLGQHKNIVNLLGACTHGGPVLVITEYCCHGDLLNFLRSKAENFLNFVMTIPNFPEPMTDYKNVSTERMFVRSDSGISSTCSDHYLDMRPVTSRPTNSALDSSSECQEDSWPLDMDDLLRFSSQVAQGLDFLAAKNCIHRDVAARNVLLTNSRVAKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFECVYTVQSDVWSYGIMLWEIFSLGKSPYPNILVDSKFYKMIKCGYQMSRPDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQRMLGETSEQQDTQEYKNIPTEAEAEQQLESCDPVKHEDESFETSCDQEEEDQPLMKPNNYQFC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 98 |
|
|
||
| 101 |
|
|
||
| 154 |
|
|
||
| 163 |
|
|
||
| 244 |
|
|
||
| 286 |
|
|
||
| 298 |
|
|
||
| 361 |
|
|
||
| 424 |
|
|
||
| 455 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Other interleukin signaling | Danio rerio |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070343 | CSF1R-related brain malformation and osteopetrosis |
