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Repository for lectin-assisted multimodality data
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MIRAGE
Fibroblast growth factor receptor 3
Summary
- UniProt ID
- Q9I8X3
- Gene Symbol
-
- fgfr3
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| receptor complex |
Sequence
MVPLCLLLYLATLVFPPVYSAHLLSPEPTDWVSSEVEVFLEDYVAGVGDTVVLSCTPQDFLLPIVWQKDGDAVSSSNRTRVGQKALRIINVSYEDSGVYSCRHAHKSMLLSNYTVKVIDSLSSGDDEDYDEDEDEAGNGNAEAPYWTRSDRMEKKLLAVPAANTVKFRCPAAGNPTPSIHWLKNGKEFKGEQRMGGIKLRHQQWSLVMESAVPSDRGNYTCVVQNKYGSIKHTYQLDVLERSPHRPILQAGLPANQTVVVGSDVEFHCKVYSDAQPHIQWLKHIEVNGSQYGPNGAPYVNVLKTAGINTTDKELEILYLTNVSFEDAGQYTCLAGNSIGYNHHSAWLTVLPAVEMEREDDYADILIYVTSCVLFILTMVIIILCRMWINTQKTLPAPPVQKLSKFPLKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRVLSMTSTDEYLDLSVPFEQYSPTCPDSNSTCSSGDDSVFAHDPLPEEPCLPKHHHSNGVIRT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 77 | N-linked (GlcNAc...) asparagine |
|
||
| 90 | N-linked (GlcNAc...) asparagine |
|
||
| 112 | N-linked (GlcNAc...) asparagine |
|
||
| 218 | N-linked (GlcNAc...) asparagine |
|
||
| 255 | N-linked (GlcNAc...) asparagine |
|
||
| 287 | N-linked (GlcNAc...) asparagine |
|
||
| 308 | N-linked (GlcNAc...) asparagine |
|
||
| 321 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR3b ligand binding and activation | Danio rerio |
| FGFR3c ligand binding and activation | Danio rerio |
| FRS-mediated FGFR3 signaling | Danio rerio |
| Phospholipase C-mediated cascade; FGFR3 | Danio rerio |
| RAF/MAP kinase cascade | Danio rerio |
| SHC-mediated cascade:FGFR3 | Danio rerio |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111160 | camptodactyly-tall stature-scoliosis-hearing loss syndrome |
