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Alpha-actinin-2
Summary
- UniProt ID
- Q9JI91
- Gene Symbol
- Actn2
- Gene ID
- 11472
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Actin-binding Calcium Cytoplasm Metal-binding Phosphoprotein Reference proteome Repeat Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| muscle contraction | ||
| microspike assembly | ||
| microspike assembly | ||
| actin cytoskeleton organization | ||
| regulation of membrane potential |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| striated muscle thin filament | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| focal adhesion |
| GO Term | Evidence Code | Reference |
|---|---|---|
| transcription coactivator activity | ||
| calcium ion binding | ||
| phosphatidylinositol-4,5-bisphosphate binding | ||
| phosphatidylinositol-4,5-bisphosphate binding | ||
| cytoskeletal protein binding |
Sequence
MNQIEPGVQYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPPYSGPGSVPGALDYTAFSSALYGESDL
Glycosylation Sites
G31852PQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Platelet degranulation | Mus musculus |
| RAF/MAP kinase cascade | Mus musculus |
| Striated Muscle Contraction | Mus musculus |
| Unblocking of NMDA receptors, glutamate binding and activation | Mus musculus |
