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Sodium/myo-inositol cotransporter

Summary

UniProt ID: Q9JKZ2
Gene Symbol: Slc5a3
Gene ID: 53881
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007594
PubChem: Q9JKZ2
Re-Glyco: Q9JKZ2

Annotation

Keyword: Cell membrane Glycoprotein Phosphoprotein Reference proteome Sodium transport Symport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
inositol metabolic process	IMP	PMID PMID
peripheral nervous system development	IMP	PMID
myo-inositol transport	IMP	PMID PMID
myo-inositol transport	IEA	GO_REF GO_REF
regulation of respiratory gaseous exchange	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

inositol metabolic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

peripheral nervous system development

localization [inference]

establishment of localization [inference]

transport [inference]

organic hydroxy compound transport [inference]

myo-inositol transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane

regulation of protein localization to membrane [inference]

positive regulation of protein localization to membrane

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

positive regulation of protein localization to membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of protein localization to membrane

positive regulation of protein localization [inference]

positive regulation of protein localization to membrane

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

regulation of reactive oxygen species metabolic process [inference]

regulation of reactive oxygen species biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of reactive oxygen species biosynthetic process

positive regulation of protein localization to membrane

regulation of cellular localization [inference]

regulation of protein localization to membrane [inference]

positive regulation of protein localization to membrane

regulation of multicellular organismal process [inference]

regulation of respiratory gaseous exchange

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
voltage-gated potassium channel complex	IDA	PMID
basolateral plasma membrane	IDA	PMID
basolateral plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

perinuclear region of cytoplasm

Displaying **all 5** entries
GO Term	Evidence Code	Reference
myo-inositol:sodium symporter activity	ISO	GO_REF
myo-inositol:sodium symporter activity	IBA	GO_REF
D-glucose:sodium symporter activity	IEA	GO_REF
potassium channel regulator activity	ISO	GO_REF
transmembrane transporter binding	ISO	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

D-glucose:sodium symporter activity

solute:sodium symporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

carbohydrate transmembrane transporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

D-glucose:sodium symporter activity

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

hexose transmembrane transporter activity [inference]

D-glucose transmembrane transporter activity [inference]

D-glucose:sodium symporter activity

polyol transmembrane transporter activity [inference]

myo-inositol transmembrane transporter activity [inference]

myo-inositol:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

D-glucose:sodium symporter activity

solute:sodium symporter activity [inference]

binding [inference]

protein binding [inference]

transmembrane transporter binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

potassium channel regulator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRAVLEAADIAVVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYNLSNTNACMVHPKANALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMTLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFTYRAPECDQPDNRPGFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTLVTKESCSQKDEPYKMQEKSILQCSENSEVISHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAALMGEREREKETENRSRYWKFIDWFCGFKSKSLSKRSLRDLMDEEAVCLQMLEETPQVKVILNIGLFAVCSLGIFMFVYFSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
232	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt
237				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Inositol transporters	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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