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Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

Summary

UniProt ID: Q9JMA9
Gene Symbol: Slc6a14
Gene ID: 56774
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007634
PubChem: Q9JMA9
RaftProt: Q9JMA9
Re-Glyco: Q9JMA9

Annotation

Keyword: Amino-acid transport Cell membrane Glycoprotein Reference proteome Symport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
beta-alanine transport	ISS	GO_REF
beta-alanine transport	ISO	GO_REF
beta-alanine transport	IBA	GO_REF
response to toxic substance	ISO	GO_REF
alanine transport	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

glycine import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane

glycine import across plasma membrane

carnitine transmembrane transport [inference]

(R)-carnitine transmembrane transport

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

glycine import across plasma membrane

neutral amino acid transport [inference]

beta-alanine transport

glycine transport [inference]

glycine import across plasma membrane

alanine transport

organic cation transport [inference]

glycine transport [inference]

glycine import across plasma membrane

carnitine transport [inference]

(R)-carnitine transport [inference]

(R)-carnitine transmembrane transport

carnitine transmembrane transport [inference]

(R)-carnitine transmembrane transport

alanine transport

organic anion transport [inference]

carboxylic acid transport [inference]

beta-alanine transport

glycine transport [inference]

glycine import across plasma membrane

alanine transport

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

beta-alanine transport

glycine transport [inference]

glycine import across plasma membrane

alanine transport

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

glycine import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane

glycine import across plasma membrane

carnitine transmembrane transport [inference]

(R)-carnitine transmembrane transport

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

nitrogen compound transport [inference]

beta-alanine transport

quaternary ammonium group transport [inference]

amino-acid betaine transport [inference]

carnitine transport [inference]

(R)-carnitine transport [inference]

(R)-carnitine transmembrane transport

carnitine transmembrane transport [inference]

(R)-carnitine transmembrane transport

glycine transport [inference]

glycine import across plasma membrane

alanine transport

modified amino acid transport [inference]

amino-acid betaine transport [inference]

carnitine transport [inference]

(R)-carnitine transport [inference]

(R)-carnitine transmembrane transport

carnitine transmembrane transport [inference]

(R)-carnitine transmembrane transport

import into cell [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

glycine import across plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	PMID
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
apical plasma membrane	IDA	PMID
apical plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
beta-alanine transmembrane transporter activity	ISS	GO_REF
beta-alanine transmembrane transporter activity	ISO	GO_REF
beta-alanine transmembrane transporter activity	IBA	GO_REF
amine transmembrane transporter activity	ISS	PMID
aromatic amino acid transmembrane transporter activity	ISO	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amine transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:sodium symporter activity [inference]

neutral, basic amino acid:sodium:chloride symporter activity

solute:sodium symporter activity [inference]

amino acid:sodium symporter activity [inference]

neutral, basic amino acid:sodium:chloride symporter activity

organic acid:sodium symporter activity [inference]

branched-chain amino acid:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

amino acid:sodium symporter activity [inference]

neutral, basic amino acid:sodium:chloride symporter activity

organic acid:sodium symporter activity [inference]

branched-chain amino acid:sodium symporter activity

amino acid transmembrane transporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:sodium symporter activity [inference]

neutral, basic amino acid:sodium:chloride symporter activity

neutral L-amino acid transmembrane transporter activity [inference]

quaternary ammonium group transmembrane transporter activity [inference]

carnitine transmembrane transporter activity [inference]

(R)-carnitine transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:sodium symporter activity [inference]

neutral, basic amino acid:sodium:chloride symporter activity

solute:sodium symporter activity [inference]

amino acid:sodium symporter activity [inference]

neutral, basic amino acid:sodium:chloride symporter activity

organic acid:sodium symporter activity [inference]

branched-chain amino acid:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

branched-chain amino acid transmembrane transporter activity [inference]

branched-chain amino acid:sodium symporter activity

alanine transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

carnitine transmembrane transporter activity [inference]

(R)-carnitine transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDRLKCPNFFKCRQKEKVTASSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISVFVAIYYNVIIAYSLYYLFASFQSVLPWANCSSWADENCSRTPIVTGCNVSIGAGEMFMNISWVNTNNLTCLNGSEVFRPGQLPSEQYWDKVTLQRSSGMDETGVVVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPAGPFWSILFFFMLLTLGLDSQFASIETITTTFQDLFPKAMKRMRVPITLGCCLILFLLGLLCVTQAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWIFWLWWRACWFVITPILLSAILVWSLVKFHRPDYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVQAEGNILQRIISCCRPASNWGPYLEKHRGERYRDMAEPAKETDHEIPTISGSTKPE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
155	N-linked (GlcNAc...) asparagine	UniProt
163	N-linked (GlcNAc...) asparagine	UniProt
174	N-linked (GlcNAc...) asparagine	UniProt
185	N-linked (GlcNAc...) asparagine	UniProt
193	N-linked (GlcNAc...) asparagine	UniProt
198	N-linked (GlcNAc...) asparagine	UniProt
298	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Amino acid transport across the plasma membrane	Mus musculus
SLC-mediated transport of neurotransmitters	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

International Collaboration

Acknowledgements