GlyCosmos Portal

Submissions

Adenosine deaminase 2

Summary

UniProt ID: Q9NZK5
Gene Symbol: ADA2 ADGF CECR1 IDGFL
Gene ID: 51816
Organism: Homo sapiens (human)

External Links

GlycoProtDB

GPDB0012621

GlyConnect

Adenosine deaminase 2

GlyGen

Q9NZK5

PubChem

Q9NZK5

The Human Metabolome Database

HMDBP11629

The O-GlcNAc Database

Q9NZK5

O-GlcNAcAtlas

Q9NZK5

Re-Glyco

Q9NZK5

Annotation

Keyword: 3D-structure Alternative splicing Disease variant Disulfide bond Glycoprotein Heparin-binding Hydrolase Metal-binding Proteomics identification Reference proteome Secreted Signal Zinc

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
adenosine catabolic process	IDA	PMID
adenosine catabolic process	IBA	GO_REF
adenosine catabolic process	IEA	GO_REF
inosine biosynthetic process	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

small molecule catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine-containing compound catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleobase-containing small molecule biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

small molecule biosynthetic process [inference]

nucleobase-containing small molecule biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleobase-containing small molecule biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside metabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

nucleobase-containing small molecule biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleobase-containing small molecule catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

small molecule metabolic process [inference]

small molecule catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

small molecule biosynthetic process [inference]

nucleobase-containing small molecule biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside metabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

nucleobase-containing small molecule biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleobase-containing small molecule catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine-containing compound metabolic process [inference]

purine nucleoside metabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine-containing compound biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine-containing compound catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

carbohydrate derivative metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside metabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside metabolic process [inference]

adenosine metabolic process [inference]

adenosine catabolic process

inosine metabolic process [inference]

inosine biosynthetic process

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

nucleoside catabolic process [inference]

purine nucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

ribonucleoside catabolic process [inference]

purine ribonucleoside catabolic process [inference]

adenosine catabolic process

carbohydrate derivative biosynthetic process [inference]

glycosyl compound biosynthetic process [inference]

nucleoside biosynthetic process [inference]

purine nucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

ribonucleoside biosynthetic process [inference]

purine ribonucleoside biosynthetic process [inference]

inosine biosynthetic process

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
extracellular region	EXP	PMID PMID
extracellular region	TAS	Reactome Reactome
extracellular region	IDA	PMID
extracellular region	IEA	GO_REF
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

azurophil granule lumen

intracellular organelle lumen [inference]

vacuolar lumen [inference]

azurophil granule lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

azurophil granule lumen

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
adenosine deaminase activity	EXP	PMID PMID
adenosine deaminase activity	IDA	PMID
adenosine deaminase activity	IBA	GO_REF
adenosine deaminase activity	IEA	GO_REF GO_REF
growth factor activity	NAS	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [inference]

adenosine deaminase activity

deaminase activity [inference]

adenosine deaminase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

adenosine receptor binding

identical protein binding [inference]

protein homodimerization activity

proteoglycan binding

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding

sulfur compound binding [inference]

heparin binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
65		30620550	G49108TO	GlyGen The O-GlcNAc Database
127	N-linked (GlcNAc...) asparagine	20147294 29391424	G11629QQ G22310AV	UniProt GlyGen GlyConnect
174	N-linked (GlcNAc...) asparagine	19159218 24190977 29391424 37074911	G12793SR G52527GH G56784JY G79666IR G83460ZZ G80920RR G90659AW G47644PP G31852PQ G11314AS G41247ZX G02815KT G92275SC	GlycoProtDB UniProt GlyGen GlyConnect
185	N-linked (GlcNAc...) asparagine	20147294 29391424	G22310AV	UniProt GlyGen GlyConnect
378	N-linked (GlcNAc...) asparagine	19159218 20147294 24190977 29391424 37074911	G12793SR G62461SM G52527GH G59536GA G00912UN G66760KM G83460ZZ G70619PT G59626AS G80920RR G62765YT G31852PQ G41247ZX	UniProt GlyGen GlyConnect