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Integrin alpha-IIb
Summary
- UniProt ID
- Q9QUM0
- Gene Symbol
- Itga2b
- Gene ID
- 16399
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0007645
- PubChem
- Q9QUM0
- Re-Glyco
- Q9QUM0
Annotation
- Keyword
- Calcium Cell adhesion Cell membrane Disulfide bond Glycoprotein Integrin Metal-binding Receptor Reference proteome Repeat Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| angiogenesis | ||
| positive regulation of leukocyte migration | ||
| positive regulation of leukocyte migration | ||
| cell-matrix adhesion | ||
| cell-matrix adhesion |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| focal adhesion | ||
| external side of plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| signaling receptor activity | ||
| identical protein binding | ||
| identical protein binding | ||
| metal ion binding |
|
|
| extracellular matrix binding |
GO Hierarchy
Sequence
MARASCAWHSLWLLQWTPLFLGPSAVPPVWALNLDSEKFSVYAGPNGSHFGFSVDFHKDKHGSVSIVVGAPRALNASQEETGAVFLCPWKANGGKCNPLLFDLRDETRNLGFQIFQTFKTGQGLGASVVSWNDVIVACAPWQHWNVLEKRDEAEKTPVGGCFLAQLQSGGRAEYSPCRANTMSSVYAESFRGDKRYCEAGFSLAVTQAGELVLGAPGGYFFLGLLARVPIENIISSYRPGTLLWHVSNQRFTYDNSNPVFFDGYRGYSVAVGEFDGDPSTTEYVSGAPTWSWTLGAVEILDSYYQPLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPKGPQALSTPTLLLTGTQLYGRFGSAIAPLGDLNRDGYNDIAVAAPYGGPSGQGQVLIFLGQSEGLSPRPSQVLDSPFPTGSGFGFSLRGAVDIDDNGYPDLIVGAYGASKVAVYRAQPVVMATVQLMVQDSLNPTLKNCVLDQTKTPVSCFNIQMCVGATGHNIPQKLHLKAELQLDLQKPRQGRRVLLLASQQASLTLSLDLGGRDKPICHTTGAFLRDEADFRDKLSPIVLSLNVSLPPEETGGAPAVVLHGETHVQEQTRIILDCGEDDLCVPQLRLTATAGDSPLLIGADNVLELKIEAANDGEGAYEAELAVHLPPGAHYMRALSNIEGFERLVCTQKKENESRVALCELGNPMKKDTRIGITMLVSVENLEEAGESVSFQLQVRSKNSQNPNSKVVMLPVAIQAEATVELRGNSFPASLVVAAEEGDREQEDLDRWVSRLEHTYELHNIGPGTVNGLRLLIHIPGQSQPSDLLYILDVQPQGGLLCSTQPSPKVDWKLSTPSPSSIRPVHHQRERRQAFLQGPKPGQQDPVLVSCDGSASCTVVECELREMVRGQRAMVTVQVMLGLSSLRQRPQEQFVLQSHAWFNVSSLPYSVPVVSLPSGQARVQTQLLRALEERAIPVWWVLVGVLGGLLLLTLLVLAMWKAGFFKRNRPPLEEDEEEE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 46 |
|
|
||
| 75 |
|
|
||
| 600 |
|
|
||
| 710 |
|
|
||
| 957 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Mus musculus |
| Fibrin formation | Mus musculus |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Mus musculus |
| Integrin cell surface interactions | Mus musculus |
| Integrin signaling | Mus musculus |
| MAP2K and MAPK activation | Mus musculus |
| Platelet degranulation | Mus musculus |
| Signal transduction by L1 | Mus musculus |
| p130Cas linkage to MAPK signaling for integrins | Mus musculus |
