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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

Summary

UniProt ID: Q9QWY8
Gene Symbol: Asap1 Ddef1 Kiaa1249 Shag1
Gene ID: 13196
Organism: Mus musculus (house mouse)

External Links

GlyGen: Q9QWY8
PubChem: Q9QWY8
The O-GlcNAc Database: Q9QWY8
O-GlcNAcAtlas: Q9QWY8
Re-Glyco: Q9QWY8

Annotation

Keyword: 3D-structure ANK repeat Alternative splicing Cilium biogenesis/degradation Cytoplasm GTPase activation Golgi apparatus Membrane Phosphoprotein Reference proteome Repeat SH3 domain Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
cilium assembly	ISS	GO_REF
cilium assembly	ISO	GO_REF
cilium assembly	IBA	GO_REF
negative regulation of dendritic spine development	IDA	PMID
protein localization to cilium	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

positive regulation of membrane tubulation

negative regulation of biological process [inference]

negative regulation of developmental process [inference]

negative regulation of dendritic spine development

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of dendritic spine development

regulation of dendritic spine development [inference]

negative regulation of dendritic spine development

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

regulation of podosome assembly [inference]

positive regulation of podosome assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

regulation of organelle assembly [inference]

regulation of podosome assembly [inference]

positive regulation of podosome assembly

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

positive regulation of membrane tubulation

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

regulation of organelle assembly [inference]

regulation of podosome assembly [inference]

positive regulation of podosome assembly

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

regulation of podosome assembly [inference]

positive regulation of podosome assembly

regulation of synapse organization [inference]

regulation of postsynapse organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of podosome assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of podosome assembly

positive regulation of membrane tubulation

regulation of plasma membrane organization [inference]

regulation of membrane tubulation [inference]

positive regulation of membrane tubulation

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GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	ISO	GO_REF
podosome	IDA	PMID PMID
podosome	IBA	GO_REF
Golgi apparatus	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

trans-Golgi network membrane

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

cell projection membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

centriolar satellite

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

podosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular membraneless organelle [inference]

podosome

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	Reference
phosphatidylserine binding	IDA	PMID
GTPase activator activity	IDA	PMID PMID PMID
GTPase activator activity	IBA	GO_REF
GTPase activator activity	IEA	GO_REF
phosphatidylinositol-4,5-bisphosphate binding	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

SH3 domain binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylserine binding

phosphatidylinositol phosphate binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

modified amino acid binding [inference]

phosphatidylserine binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRSSASRLSSFSSRDSLWNRMPDQISVSEFIAETTEDYNSPTTSSFTTRLHNCRNTVTLLEEALDQDRTALQKVKKSVKAIYNSGQDHVQNEENYAQVLDKFGSNFLSRDNPDLGTAFVKFSTLTKELSTLLKNLLQGLSHNVIFTLDSLLKGDLKGVKGDLKKPFDKAWKDYETKFTKIEKEKREHAKQHGMIRTEITGAEIAEEMEKERRLFQLQMCEYLIKVNEIKTKKGVDLLQNLIKYYHAQCNFFQDGLKTADKLKQYIEKLAADLYNIKQTQDEEKKQLTALRDLIKSSLQLDPKEVGGLYVASRANSSRRDSQSRQGGYSMHQLQGNKEYGSEKKGFLLKKSDGIRKVWQRRKCAVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYIAWISVLTNSKEEALTMAFRGEQSTGENSLEDLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHRFSRKTCASSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEPGQELGETALHLAVRTADQTSLHLVDFLVQNCGNLDKQTSVGNTVLHYCSMYGKPECLKLLLRSKPTVDIVNQNGETALDIAKRLKATQCEDLLSQAKSGKFNPHVHVEYEWNLRQDEMDESDDDLDDKPSPIKKERSPRPQSFCHSSSISPQDKLALPGFSTPRDKQRLSYGAFTNQIFASTSTDLPTSPTSEAPPLPPRNAGKGPTGPPSTLPLGTQTSSGSSTLSKKRPPPPPPGHKRTLSDPPSPLPHGPPNKGAIPWGNDVGPLSSSKTANKFEGLSQQASTSSAKTALGPRVLPKLPQKVALRKTETSHHLSLDRTNIPPETFQKSSQLTELPQKPPLGELPPKPVELAPKPQVGELPPKPGELPPKPQLGDLPPKPQLSDLPPKPQMKDLPPKPQLGDLLAKSQAGDVSAKVQPPSEVTQRSHTGDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHILSD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	PubMed ID	GlyTouCan ID	Source
546			GlyGen
818	22517741 34678516 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database
823	22517741 34678516 40021952 40885482	G49108TO	GlyGen The O-GlcNAc Database