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Sodium/glucose cotransporter 1

Summary

UniProt ID: Q9QXI6
Gene Symbol: Slc5a1 Nagt Sglt1
Gene ID: 20537
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0007663
Re-Glyco: Q9QXI6

Annotation

Keyword: Cell membrane Disulfide bond Glycoprotein Proteomics identification Reference proteome Sodium transport Sugar transport Symport Transmembrane helix

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
carbohydrate utilization	IEA	GO_REF
transepithelial water transport	IEA	GO_REF
D-glucose import across plasma membrane	IEA	GO_REF
sodium ion import across plasma membrane	IEA	GO_REF
transport across blood-brain barrier	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport [inference]

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

response to stimulus [inference]

response to nutrient levels [inference]

carbohydrate utilization

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport [inference]

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

vascular transport [inference]

transport across blood-brain barrier

fluid transport [inference]

water transport [inference]

transepithelial water transport

epithelial fluid transport [inference]

transepithelial water transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport [inference]

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

transepithelial transport [inference]

epithelial fluid transport [inference]

transepithelial water transport

import into cell [inference]

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
early endosome	IEA	GO_REF
Golgi apparatus
cell-cell junction	IEA	GO_REF
brush border membrane	IEA	GO_REF
nuclear membrane

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

nuclear membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	Reference
water transmembrane transporter activity	IEA	GO_REF
D-glucose:sodium symporter activity	IEA	GO_REF GO_REF
alpha-glucoside transmembrane transporter activity	IEA	GO_REF
galactose:sodium symporter activity	IEA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

water transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

carbohydrate transmembrane transporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

hexose transmembrane transporter activity [inference]

galactose transmembrane transporter activity [inference]

galactose:sodium symporter activity

D-glucose transmembrane transporter activity [inference]

D-glucose:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

carbohydrate derivative transmembrane transporter activity [inference]

glucoside transmembrane transporter activity [inference]

alpha-glucoside transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDSSTLSPAVTATDAPIPSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVLGWIFVPIYIKAGVVTMPEYLRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPRADSFHIFRDPITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLIGISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFVISVITILIISFLTKPIPDVHLYRLCWSLRNSKEERIDLDAGEEEDIPEDSKDTIEIDTEAPQKKKGCFRRAYDLFCGLDQDKGPKMTKEEEEAMKMKMTDTSEKPLWRTVVNINGIILLAVAVFCHAYFA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
248				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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